92107

O-Acetyl-L-carnitine hydrochloride

analytical standard

• Synonyme(s) : (R)-3-Acetoxy-4-(trimethylammonio)butyrate hydrochloride, ALC, ALCAR, R-(−)-2-Acetyloxy-3-carboxy-N,N,N-trimethyl-1-propanaminium chloride
• Formule empirique (notation de Hill): C₉H₁₇NO₄ · HCl
• Numéro CAS: 5080-50-2
• Poids moléculaire : 239.70
• Numéro Beilstein : 4340103
• Numéro MDL: MFCD00082230
• Code UNSPSC : 41116107
• Nomenclature NACRES : NB.21

Propriétés

• Qualité: analytical standard
• Niveau de qualité: 100
• Pureté: ≥96.0% (HPLC); 96.0-104.0% (AT)
• Forme: powder or crystals
• Activité optique: [α]/D -27.0±2.0°, c = 1 in H₂O
• Durée de conservation: limited shelf life, expiry date on the label
• Couleur: white to off-white
• Application(s): clinical testing
• Format: neat
• Température de stockage: 2-8°C
• Chaîne SMILES: C[N+](C)(C)C[C@H](OC(C)=O)CC(O)=O.[Cl-]
• InChI: 1S/C9H17NO4.ClH/c1-7(11)14-8(5-9(12)13)6-10(2,3)4;/h8H,5-6H2,1-4H3;1H/t8-;/m1./s1
• Clé InChI: JATPLOXBFFRHDN-DDWIOCJRSA-N

Description

Description générale

Acetyl carnitine is one of the major acylcarnitines produced during the transport of long-chain fatty acids in the body.

Application

O-Acetyl-L-carnitine hydrochloride may be used as a precursor for the preparation of O-Acetyl-L-carnitine, which in turn may be used as an analytical reference standard for the determination of the analyte in biological samples by hydrophilic interaction liquid chromatography-tandem mass spectrometry (HILIC-MS/MS) technique.

Actions biochimiques/physiologiques

Endogenous mitochondrial metabolite that transports acetyl groups across the mitochondrial membrane. Exogenous acetylcarnitine enhances mitochondrial function in aged rats. As an acetate donor to coenzyme A, it increases the central and peripheral acetylcholine synthesis and function. Acetylcarnitine has antinociceptive activity that may be mediated by enhanced activity of muscarinic cholinergic receptors or mGlu2 glutamate receptors.

Produits recommandés

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Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H315 - H319 - H335
• Conseils de prudence: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Classification des risques: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organes cibles: Respiratory system
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable