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72706

L-Leucine

Name: <SC>L</SC>-Leucine
Brand: SIAL

tested according to Ph. Eur.

Synonyme(s) :

Leucinum, (S)-2-Amino-4-methylpentanoic acid

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About This Item

Formule linéaire :

(CH₃)₂CHCH₂CH(NH₂)CO₂H

Numéro CAS:

61-90-5

Poids moléculaire :

131.17

Numéro Beilstein :

1721722

Numéro CE :

200-522-0

Numéro MDL:

MFCD00002617

Code UNSPSC :

12352209

ID de substance PubChem :

329764290

Agence

USP/NF
tested according to Ph. Eur.

Pureté

98.5-101.0%

Forme

powder

Couleur

white

Pf

>300 °C (lit.)

Chaîne SMILES

CC(C)C[C@H](N)C(O)=O

InChI

1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1

Clé InChI

ROHFNLRQFUQHCH-YFKPBYRVSA-N

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Code de la classe de stockage

13 - Non Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

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Certificats d'analyse (COA)

Lot/Batch Number

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The organization of prefrontal-subthalamic inputs in primates provides an anatomical substrate for both functional specificity and integration: implications for Basal Ganglia models and deep brain stimulation.

William I A Haynes et al.

The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(11), 4804-4814 (2013-03-15)

The identification of a hyperdirect cortico-subthalamic nucleus connection highlighted the important role of the subthalamic nucleus (STN) in regulating behavior. However, this pathway was shown primarily from motor areas. Hyperdirect pathways associated with cognitive and motivational cortical regions are particularly

Targeting amino acid transport in metastatic castration-resistant prostate cancer: effects on cell cycle, cell growth, and tumor development.

Qian Wang et al.

Journal of the National Cancer Institute, 105(19), 1463-1473 (2013-09-21)

L-type amino acid transporters (LATs) uptake neutral amino acids including L-leucine into cells, stimulating mammalian target of rapamycin complex 1 signaling and protein synthesis. LAT1 and LAT3 are overexpressed at different stages of prostate cancer, and they are responsible for

Occurrence of methionine-enkephalin-Arg6-Gly7-Leu8 with methionine-enkephalin, leucine-enkephalin and methionine-enkephalin-Arg6-Phe7 in human gastric antrum.

M Sakamoto et al.

The Journal of clinical endocrinology and metabolism, 56(1), 202-204 (1983-01-01)

Recent studies on the nucleotide sequence of cloned DNA complementary to mRNA for preproenkephalin from bovine adrenal medulla and human pheochromocytoma have revealed that this precursor molecule contains four copies of methionine-enkephalin (Met-Enk) and one copy each of leucine-enkephalin (Leu-Enk)

Methionine-enkephalin and leucine-enkephalin in human sympathoadrenal system and pheochromocytoma.

T Yoshimasa et al.

The Journal of clinical investigation, 69(3), 643-650 (1982-03-01)

To elucidate the physiological and pathophysiological significance of methionine- and leucine-enkephalin (Met-and Leu-enkephalin, respectively) in human sympathoadrenal system, the contents of these peptides in normal human sympathetic nervous system, adrenal medulla, and pheochromocytomas were determined by specific radioimmunoassays combined with

The role of small leucine-rich proteoglycans in collagen fibrillogenesis.

Sebastian Kalamajski et al.

Matrix biology : journal of the International Society for Matrix Biology, 29(4), 248-253 (2010-01-19)

Small leucine-rich proteoglycans/proteins (SLRPs) are associated with collagen fibril formation, and therefore important for the proper formation of extracellular matrices. SLRPs are differentially expressed in tissues and during pathological conditions, contributing to the development of connective tissue properties. The binding

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Chromatograms

HPLC Analysis of Leucine Enantiomers on Astec^® CHIROBIOTIC^® T (25 °C)

application for HPLC

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