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Key Documents

235989

Sigma-Aldrich

Brij® L4

average Mn ~362

Synonyme(s) :

Polyethylene glycol dodecyl ether, Polyoxyethylene (4) lauryl ether

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About This Item

Formule linéaire :
(C20H42O5)n
Numéro CAS:
Numéro MDL:
Code UNSPSC :
12161900
ID de substance PubChem :
Nomenclature NACRES :
NA.21

Description

non-ionic

Niveau de qualité

Poids mol.

average Mn ~362

Indice de réfraction

n20/D 1.451 (lit.)

Densité

0.95 g/mL at 25 °C (lit.)

HLB

9

Chaîne SMILES 

CCCCCCCCCCCCOCCOCCOCCOCCO

InChI

1S/C20H42O5/c1-2-3-4-5-6-7-8-9-10-11-13-22-15-17-24-19-20-25-18-16-23-14-12-21/h21H,2-20H2,1H3

Clé InChI

WPMWEFXCIYCJSA-UHFFFAOYSA-N

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Description générale

Brij® L4 is a non-ionic surfactant. It comprises an alkyl (C12) tail attached to an oxyethylene headgroup.

Application

Brij® L4 has been used:
  • as a surfactant for the synthesis of copper(I) oxide (Cu2O) spherical nanoparticles using a microemulsion technique
  • as a non-ionic surfactant for preparing reverse micelles to synthesize Pt3Co alloy nanoparticles
  • as a surfactant to enhance the efficiency of interfacial coupling of hydrophobic materials and to make hydrogel

Actions biochimiques/physiologiques

Brij® L4 exhibits amphiphilic properties. Brij L4 contains hydrophobic and hydrophilic regions that can form micelles and disperse hydrophobic drugs into the core of micelles. This in turn enhances drug solubility. Brij L4 also elicits a strong inhibitory effect against breast cancer resistance protein (BCRP) mediated drug efflux. It inhibits Taq adsorption better when compared to other commonly used surfactants. Brij L4 supports droplet polymerase chain reaction (PCR) in picoliter reaction volumes at standard Taq concentrations.

Informations légales

Brij is a registered trademark of Croda International PLC

Pictogrammes

Exclamation markEnvironment

Mention d'avertissement

Warning

Mentions de danger

Classification des risques

Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

dust mask type N95 (US), Eyeshields, Gloves


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