15527

Glycine

meets analytical specification of Ph. Eur., BP, USP, 99-101% (based on anhydrous substance)

• Synonyme(s) : Acide aminoacétique, Acide aminoéthanoïque, Glycocolle
• Formule linéaire : NH₂CH₂COOH
• Numéro CAS: 56-40-6
• Poids moléculaire : 75.07
• Numéro Beilstein : 635782
• Numéro CE : 200-272-2
• Numéro MDL: MFCD00008131
• Code UNSPSC : 12352209
• eCl@ss : 32160406
• ID de substance PubChem : 57647473
• Nomenclature NACRES : NA.21

Propriétés

• Niveau de qualité: 200
• Pureté: 99-101% (based on anhydrous substance)
• Forme: crystalline powder
• Qualité: meets analytical specification of Ph. Eur., BP, USP
• Technique(s): IR spectroscopy: suitable
• Impuretés: hydrolyzable substances, complies; organic volatile impurities, complies (GC); residual solvents, complies; ≤0.001% heavy metals (as Pb); ≤1.0% ninhydrin-positive substances
• Résidus de calcination: ≤0.1% (as SO₄)
• Perte: ≤0.2% loss on drying, 105 °C, 2 h
• Couleur: white
• pH: 5.9-6.4 (20 °C, 5%)
• pKa (25 °C): (1) 2.35, (2) 9.60; 2.35
• Pf: 240 °C (dec.) (lit.)
• Solubilité: H₂O: soluble 25 gm in 100 ml at 25 degrees c; H₂O: soluble 39.1 gm in 100 ml at 50 degrees c; alcohol: soluble 0.06 gm in 100 gm (Absolute); pyridine: soluble 164 parts; alcohol: very slightly soluble; diethyl ether: very slightly soluble
• Traces d'anions: chloride (Cl^-): ≤50 mg/kg; sulfate (SO₄^2-): ≤50 mg/kg
• Adéquation: complies for appearance of solution; complies for reaction against H₂SO₄; in accordance for identity (IR)
• Chaîne SMILES: NCC(O)=O
• InChI: 1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
• Clé InChI: DHMQDGOQFOQNFH-UHFFFAOYSA-N
• Informations sur le gène: rat ... Grin2a(24409)

Description

Application

Glycine was used for preparing platelets from whole-blood samples and study the stimulation of cytokine expression in leukocytes. It was used for biochemical and tolerance tests.

Actions biochimiques/physiologiques

Glycine has a pivotal role in lowering the plasma lipid levels in diabetic and obese patients by activating the CNS. During brain hypoxia glycine can stabilize the energetics disturbances in brain mitochondria. It also increases the in vitro development of porcine blastocysts when used along with glucose.

Neurotransmetteur inhibiteur de la moelle épinière, régulateur allostérique des récepteurs du NMDA.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)