00180585

Hyperoside

primary reference standard

• Synonyme(s) : Quercetin 3-D-galactoside, 3,3′,4′,5,7-Pentahydroxyflavone 3-D-galactoside, Hyperin, Hyperoside
• Formule empirique (notation de Hill): C₂₁H₂₀O₁₂
• Numéro CAS: 482-36-0
• Poids moléculaire : 464.38
• Numéro Beilstein : 5784795
• Numéro CE : 207-580-6
• Numéro MDL: MFCD00016933
• Code UNSPSC : 85151701
• ID de substance PubChem : 329747012
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: primary reference standard
• Durée de conservation: limited shelf life, expiry date on the label
• Fabricant/nom de marque: HWI
• Technique(s): HPLC: suitable; gas chromatography (GC): suitable
• Chaîne SMILES: OC[C@H]1O[C@@H](OC2=C(Oc3cc(O)cc(O)c3C2=O)c4ccc(O)c(O)c4)[C@H](O)[C@@H](O)[C@H]1O
• InChI: 1S/C21H20O12/c22-6-13-15(27)17(29)18(30)21(32-13)33-20-16(28)14-11(26)4-8(23)5-12(14)31-19(20)7-1-2-9(24)10(25)3-7/h1-5,13,15,17-18,21-27,29-30H,6H2/t13-,15+,17+,18-,21+/m1/s1
• Clé InChI: OVSQVDMCBVZWGM-DTGCRPNFSA-N

Description

Description générale

Hyperoside is a flavonol glycoside compound used in Traditional Chinese medicine for its various beneficial effects, such as anti-inflammatory, anti-oxidant, anti-viral, and anti-cancer.

Produced and qualified by HWI pharma services GmbH.
Exact content measured by quantitative NMR can be found on the certificate.

Application

The primary reference standard can be used for identification, assay, and purity testing, method development, and validation.

It can also be used as follows:

• Development of an ultra performance liquid chromatography-mass spectrometric method to determine hyperoside in rat plasma samples following sample treatment by protein precipitation and liquid-liquid extraction
• Multi-residue analysis of hyperoside, isoquercitrin, and eleutheroside E in botanical samples of Apocynum venetum L. and Eleutherococcus senticosus used in traditional Chinese medicine by HPLC combined with diode array detection (DAD)
• Ionic liquid vacuum microwave-assisted extraction (ILVMAE) of rutin, hyperoside, and hesperidin from Sorbus tianschanica leaf samples for their subsequent quantification by HPLC
• Simultaneous detection and quantification of vitexin, rutin, hyperoside, and quercetin in hawthorn flower and leaf extract samples using high-performance liquid chromatography combined with spectrophotometric detection (HPLC-UV)

Actions biochimiques/physiologiques

Protects against peroxide-induced oxidative damage to cells by scavenging reactive oxygen species and enhancing activity of anti-oxidant enzymes, in particular, catalase and glutathione peroxidase.

Autres remarques

A flavonol glycoside widely distribute in plants, including mimosa and St. John′s wort.

This compound is commonly found in plants of the genus: crataegus eucalyptus hypericum sambucus

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H302
• Conseils de prudence: P264 - P270 - P301 + P312 - P501
• Classification des risques: Acute Tox. 4 Oral
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable