MABC158

Anti-hyaluronan synthase 1 Antibody, clone 12A2.3

clone 12A2.3, from mouse

• Synonyme(s) : Hyaluronan synthase 1, Hyaluronate synthase 1, Hyaluronic acid synthase 1, HA synthase 1, HuHAS1
• Code UNSPSC : 12352203
• eCl@ss : 32160702
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: mouse
• Niveau de qualité: 100
• Forme d'anticorps: purified immunoglobulin
• Type de produit anticorps: primary antibodies
• Clone: 12A2.3, monoclonal
• Espèces réactives: human
• Technique(s): immunohistochemistry: suitable; western blot: suitable
• Isotype: IgMκ
• Numéro d'accès NCBI: NP_001514
• Numéro d'accès UniProt: Q92839
• Conditions d'expédition: wet ice
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... HAS1(3036)

Description

Description générale

Hyaluronan synthase 1 (HAS1) is one of three enzymes, located at the plasma membrane, that synthesizes the glycosaminoglycan hyaluronan or hyaluronic acid (HA). Hyaluronan is involved in cell proliferation, differentiation, angiogenesis, and tumor development, among other cellular processes.

Spécificité

This antibody recognizes the cytoplasmic domain of hyaluronan synthase 1.

Immunogène

Epitope: Cytoplasmic domain

KLH-conjugated linear peptide corresponding to the cytoplasmic domain of human hyaluronan synthase 1.

Application

Anti-hyaluronan synthase 1 Antibody, clone 12A2.3 is a highly specific mouse monoclonal antibody, that targets Hyaluronan synthase 1 & has been tested in western blotting & IHC.

Immunohistochemistry Analysis: A 1:200 dilution from a representative lot detected hyaluronan synthase 1 in human ovarian cancer tissues.

Research Category
Apoptosis & Cancer

Research Sub Category
Apoptosis - Additional

Qualité

Evaluated by Western Blotting in HL-60 cell lysate.

Western Blotting Analysis: 1 µg/mL of this antibody detects hyaluronan synthase 1 in 10 µg of HL-60 cell lysate.

Description de la cible

~70 kDa observed

Forme physique

Format: Purified

Purified mouse IgMκ supernatant in buffer containing PBS with 0.05% sodium azide.

Stockage et stabilité

Stable for 1 year at 2-8°C from date of receipt.

Remarque sur l'analyse

Control
HL-60 cell lysate

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable