MAB8906
Anti-Measles Antibody, nucleoprotein, clone 83KKII
clone 83KKII, Chemicon®, from mouse
Synonyme(s) :
Rubeola
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About This Item
Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41
Produits recommandés
Source biologique
mouse
Niveau de qualité
Forme d'anticorps
purified immunoglobulin
Type de produit anticorps
primary antibodies
Clone
83KKII, monoclonal
Espèces réactives
human
Fabricant/nom de marque
Chemicon®
Technique(s)
ELISA: suitable
immunocytochemistry: suitable
immunofluorescence: suitable
Isotype
IgG
Conditions d'expédition
wet ice
Description générale
Measles is a highly contagious, acute febrile illness that has been one of the most common viral diseases of young children. Although measles has been effectively controlled in recent years by the use of live attenuated virus vaccines, measles continues to have a serious impact on human health as evidenced by its continued persistence in developing countries. Measles is characterized by a prodrome illness with rapidly rising fever that culminates in a generalized macular-papular rash. The appearance of Koplik′s spots on the mouth epithelium during or after the prodromal phase is pathognomonic for measles. The measles virus belongs to the family Paramyxoviridae, and is a member of the genus Morbillivirus. Measles is an enveloped, pleomorphic virus ranging from 100 to 250 nm in diameter with a single stranded linear RNA. Infected cells contain large amounts of nucleoprotein antigen which is the major internal protein of measles virus. Consequently, the dominant part of the antibody response to measles virus involves the nucleoprotein antigen.
Spécificité
MAB8906 recognizes the measles nucleoprotein by capture EIA.
Immunogène
Epitope: Nucleoprotein
Application
Capture ELISA: A 1:5,000-1:10,000 dilution of a previous lot was used in ELISA.
Indirect Immunofluorescence: A previous lot of this antibody was used on indirect immunofluorescence.
Immunocytochemistry Analysis: A 1:100 dilution from a representative lot detected the measles nucleoprotein in cells infected with measles virus.
Optimal working dilutions must be determined by end user.
Indirect Immunofluorescence: A previous lot of this antibody was used on indirect immunofluorescence.
Immunocytochemistry Analysis: A 1:100 dilution from a representative lot detected the measles nucleoprotein in cells infected with measles virus.
Optimal working dilutions must be determined by end user.
Research Category
Infectious Diseases
Infectious Diseases
Research Sub Category
Infectious Diseases - Viral
Infectious Diseases - Viral
This Anti-Measles Antibody, nucleoprotein, clone 83KKII is validated for use in ELISA, IF for the detection of Measles.
Forme physique
Format: Purified
Protein A purified
Purified mouse monoclonal IgG in buffer containing liquid in PBS with 0.1% sodium azide.
Stockage et stabilité
Stable for 1 year at from date of receipt.
Remarque sur l'analyse
Control
Measles Control Slides, Catalogue Number 5031-5
Measles Control Slides, Catalogue Number 5031-5
Autres remarques
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Informations légales
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Clause de non-responsabilité
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Code de la classe de stockage
10 - Combustible liquids
Classe de danger pour l'eau (WGK)
WGK 2
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Certificats d'analyse (COA)
Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".
Déjà en possession de ce produit ?
Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.
Measles virus entry through the signaling lymphocyte activation molecule governs efficacy of mantle cell lymphoma radiovirotherapy.
Miest, TS; Frenzke, M; Cattaneo, R
Molecular Therapy null
Daria Jacob et al.
PloS one, 9(1), e86658-e86658 (2014-01-30)
Yeasts are largely used as bioreactors for vaccine production. Usually, antigens are produced in yeast then purified and mixed with adjuvants before immunization. However, the purification costs and the safety concerns recently raised by the use of new adjuvants argue
Adherens junction protein nectin-4 is the epithelial receptor for measles virus.
Muhlebach, MD; Mateo, M; Sinn, PL; Prufer, S; Uhlig, KM; Leonard, VH; Navaratnarajah et al.
Nature null
Lung involvement in childhood measles: severe immune dysfunction revealed by quantitative immunohistochemistry.
Talib Moyses Moussallem,Fernanda Guedes,Elaine Raniero Fernandes,Carla Pagliari et al.
Human Pathology null
Ludmila Perelygina et al.
Frontiers in immunology, 12, 796065-796065 (2022-01-11)
Rubella virus (RuV) has recently been found in association with granulomatous inflammation of the skin and several internal organs in patients with inborn errors of immunity (IEI). The cellular tropism and molecular mechanisms of RuV persistence and pathogenesis in select
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