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Key Documents

MAB5780

Sigma-Aldrich

Anti-NMDAR2B Antibody

ascites fluid, clone 1E4.25A4, Chemicon®

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

mouse

Niveau de qualité

Forme d'anticorps

ascites fluid

Clone

1E4.25A4, monoclonal

Espèces réactives

mouse, rabbit, rat

Fabricant/nom de marque

Chemicon®

Technique(s)

western blot: suitable

Isotype

IgG1

Numéro d'accès NCBI

Numéro d'accès UniProt

Conditions d'expédition

dry ice

Modification post-traductionnelle de la cible

unmodified

Spécificité

NMDAR2B, N-terminal. By Western blot the antibody reacts with bands at ~170 and ~48 kDa on rat brain lystate. An additional band at ~100 kDa may be seen depending on sample and antibody concentration used.

Immunogène

Recombinant protein from rat NMDAR2B.

Application

Anti-NMDAR2B Antibody detects level of NMDAR2B & has been published & validated for use in WB.
Research Category
Neuroscience
Research Sub Category
Neurotransmitters & Receptors
Western blot: 1:500-1:1,000 on rat brain lysate.

Optimal working dilutions must be determined by end user.

Forme physique

Liquid

Stockage et stabilité

Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

Informations légales

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


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Peter Svensson et al.
Pain, 148(3), 473-480 (2010-01-13)
Injection of nerve growth factor (NGF) into the masseter muscle is not painful but does induce a localized, quick onset ( approximately 1h) and long-lasting mechanical sensitization in healthy human subjects. We tested the hypothesis that human NGF mechanically sensitizes
Zhao-hui Xu et al.
PloS one, 7(10), e48741-e48741 (2012-11-03)
Fragile X syndrome is a common inherited form of mental retardation caused by the lack of fragile X mental retardation protein (FMRP) because of Fmr1 gene silencing. Serotonin (5-HT) is significantly increased in the null mutants of Drosophila Fmr1, and
Han Zhao et al.
Brain and behavior, 8(7), e01004-e01004 (2018-06-02)
It is known that an interruption of acoustic input in early life will result in abnormal development of the auditory system. Here, we further show that this negative impact actually spans beyond the auditory system to the hippocampus, a system
Wen Yu et al.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 17(3), 1253-1270 (2020-04-17)
The balance of major excitatory (glutamate, Glu) and inhibitory (γ-aminobutyric acid, GABA), named as E/I neurotransmission, is critical for proper information processing. Anxiety-like responses upon stress are accompanied by abnormal alterations in the formation and function of synapses, resulting in

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