MAB3864
Anti-DNA/Histone H1 Antibody
Chemicon®, from mouse
Synonyme(s) :
Anti-H1.4, Anti-H1E, Anti-H1F4, Anti-H1s-4, Anti-HIST1H1E, Anti-RMNS, Anti-dJ221C16.5
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About This Item
Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41
Produits recommandés
Source biologique
mouse
Niveau de qualité
Forme d'anticorps
purified antibody
Type de produit anticorps
primary antibodies
Clone
monoclonal
Réactivité de l'espèce (prédite par homologie)
all
Fabricant/nom de marque
Chemicon®
Technique(s)
ELISA: suitable
flow cytometry: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable
Isotype
IgG2a
Numéro d'accès NCBI
Numéro d'accès UniProt
Conditions d'expédition
wet ice
Modification post-traductionnelle de la cible
unmodified
Informations sur le gène
human ... H1-1(3024)
Spécificité
Reacts with DNA/Histone 1. The antibody can be used to stain nuclei of all species and to identify necrosis. By immunohistochemistry, the antibody shows dense staining of nuclei with no staining of nucleoli observed.
Immunogène
Human Raji cell nuclei
Application
Anti-DNA/Histone H1 Antibody is a high quality Mouse Monoclonal Antibody for the detection of DNA/Histone H1 & has been validated in ELISA, FC, ICC & IHC.
Immunocytochemistry: 5-10 μg/mL on 2% paraformaldehyde fixed cells (10 minutes at room temperature)
Immunohistochemistry: 5-10 μg/mL on paraformaldehyde or B5 fixed tissue sections.
Flow cytometry: 5-10 μg/mL using 2% paraformaldehyde fixed cells.
ELISA, direct and indirect
Optimal working dilutions must be determined by end user.
STAINING PATTERN:
Nuclear staining observed. Dense staining of nuclei. No staining of nucleoli.
Immunohistochemistry: 5-10 μg/mL on paraformaldehyde or B5 fixed tissue sections.
Flow cytometry: 5-10 μg/mL using 2% paraformaldehyde fixed cells.
ELISA, direct and indirect
Optimal working dilutions must be determined by end user.
STAINING PATTERN:
Nuclear staining observed. Dense staining of nuclei. No staining of nucleoli.
Research Category
Epigenetics & Nuclear Function
Epigenetics & Nuclear Function
Research Sub Category
Histones
Histones
Forme physique
Format: Purified
Protein A purified culture supernatant. Liquid in PBS
Stockage et stabilité
Maintain at -20°C in undiluted aliquots for up to 6 months from date of receipt. Avoid repeated freeze/thaw cycles.
Autres remarques
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Informations légales
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Clause de non-responsabilité
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Code de la classe de stockage
12 - Non Combustible Liquids
Classe de danger pour l'eau (WGK)
WGK 2
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Certificats d'analyse (COA)
Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".
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Neutrophil Responses to Sterile Implant Materials.
Jhunjhunwala, S; Aresta-DaSilva, S; Tang, K; Alvarez, D; Webber, MJ; Tang, BC; Lavin et al.
Testing null
Gang Liu et al.
Mucosal immunology, 12(4), 862-873 (2019-04-13)
Extra-intestinal manifestations (EIM) are common in inflammatory bowel disease (IBD). One such EIM is sub-clinical pulmonary inflammation, which occurs in up to 50% of IBD patients. In animal models of colitis, pulmonary inflammation is driven by neutrophilic infiltrations, primarily in
Wenxiang Shen et al.
Animals : an open access journal from MDPI, 12(9) (2022-05-15)
Endometritis is a common disease that affects the production in dairy cows and leads to severe losses in the dairy industry. Neutrophil extracellular traps (NETs) formation promotes pathogenic invasions of the lumen of the tissue, leading to inflammatory diseases such
A comparative autoradiographic study demonstrating differential intratumor localization of monoclonal antibodies to cell surface (Lym-1) and intracellular (TNT-1) antigens.
Chen, F M, et al.
Journal of Nuclear Medicine, 31, 1059-1066 (1990)
Neila Álvarez de Haro et al.
Fish & shellfish immunology, 119, 209-219 (2021-08-27)
Neutrophils release chromatin extracellular traps (ETs) as part of the fish innate immune response to counter the threats posed by microbial pathogens. However, relatively little attention has been paid to this phenomenon in many commercially farmed species, despite the importance
Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..
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