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Merck
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Key Documents

MAB3478

Sigma-Aldrich

Anti-1-cys Peroxiredoxin Antibody, clone 8H11

ascites fluid, clone 8H11, Chemicon®

Synonyme(s) :

aiPLA2, Peroxiredoxin 6, Non-selenium Glutathione Peroxidase

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

mouse

Niveau de qualité

100

Forme d'anticorps

ascites fluid

Type de produit anticorps

primary antibodies

Clone

8H11, monoclonal

Espèces réactives

human, rat

Fabricant/nom de marque

Chemicon®

Technique(s)

immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable

Isotype

IgM

Numéro d'accès NCBI

NM_004905.2

Numéro d'accès UniProt

P30041

Conditions d'expédition

dry ice

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... PRX(57716)

Description générale

1-Cys-Peroxiredoxin is a cytosolic protein that is involved in the regulation of cellular redox potential. 1-Cys peroxiredoxin is a bifunctional enzyme with glutathione peroxidase and phospholipase A2 activities (Chen, 2000). It can reduce hydrogen peroxide, short chain fatty acids, and phospholipid hydroperoxides and is believed to play a role in phospholipid turnover as well as in the protection against oxidative injury.

Spécificité

1-Cys-Peroxiredoxin (Prx VI).

Immunogène

Recombinant human 1-Cys peroxiredoxin.

Application

Detect 1-cys Peroxiredoxin using this Anti-1-cys Peroxiredoxin Antibody, clone 8H11 validated for use in WB, IC, IH.
Research Category
Neuroscience
Research Sub Category
Oxidative Stress
Western blot on rat lung lysate (24 kDa) or recombinant human protein.

Immunohistochemistry on 4% paraformaldehyde fixed rat lung tissue.

Immunocytochemistry on rat type II alveolar epithelial cells.

Optimal working dilutions must be determined by the end user.

Forme physique

Ascites fluid. Liquid.

Stockage et stabilité

Maintain at -20°C in undiluted aliquots up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

Informations légales

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

A B Fisher et al.
American journal of physiology. Lung cellular and molecular physiology, 280(4), L748-L754 (2001-03-10)
This study evaluated the role of a lysosomal-type phospholipase A2 (aiPLA(2)) in the degradation of internalized dipalmitoylphosphatidylcholine (DPPC) and in phospholipid synthesis by the rat lung. Uptake and degradation of DPPC were measured in isolated perfused rat lungs over 3
Seunghyi Kook et al.
The Journal of biological chemistry, 291(16), 8414-8427 (2016-02-26)
The Hermansky Pudlak syndromes (HPS) constitute a family of disorders characterized by oculocutaneous albinism and bleeding diathesis, often associated with lethal lung fibrosis. HPS results from mutations in genes of membrane trafficking complexes that facilitate delivery of cargo to lysosome-related

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