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Merck
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Key Documents

MAB1056

Sigma-Aldrich

Anti-Neutrophil Elastase Antibody, clone AHN-10

ascites fluid, clone AHN-10, Chemicon®

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702

Source biologique

mouse

Forme d'anticorps

ascites fluid

Type de produit anticorps

primary antibodies

Clone

AHN-10, monoclonal

Espèces réactives

human

Fabricant/nom de marque

Chemicon®

Technique(s)

immunocytochemistry: suitable
immunoprecipitation (IP): suitable
radioimmunoassay: suitable

Isotype

IgG1

Numéro d'accès NCBI

Numéro d'accès UniProt

Conditions d'expédition

dry ice

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... SERP1(27230)

Spécificité

Reacts specifically with human neutrophil elastase and not with the 3 homologous neutrophil neutral serine proteases, cathepsin G, esterase N and proteinase 3. Inhibits the elastinolytic activity of elastase. Elastase is felt to play an important role in a number of disease states.

Application

Anti-Neutrophil Elastase Antibody, clone AHN-10 detects level of Neutrophil Elastase & has been published & validated for use in IP, RIA & IC.
Immunoprecipitation

Immunocytochemistry

RIA

Optimal working dilutions must be determined by end user.
Research Category
Inflammation & Immunology
Research Sub Category
Inflammation & Autoimmune Mechanisms

Stockage et stabilité

Maintain in convenient aliquots at -20°C or colder for up to 12 months. Avoid thawing and refreezing.

Informations légales

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

M Brittany Johnson et al.
Cellular microbiology, 17(5), 648-665 (2014-10-28)
During gonorrhoeal infection, there is a heterogeneous population of Neisseria gonorrhoeae (Gc) varied in their expression of opacity-associated (Opa) proteins. While Opa proteins are important for bacterial attachment and invasion of epithelial cells, Opa+ Gc has a survival defect after
Julia Mayerle et al.
Gastroenterology, 129(4), 1251-1267 (2005-10-19)
Cadherins play an important role in cell-cell contact formation at adherens junctions. During the course of acute pancreatitis, adherens junctions are known to dissociate-a requirement for the interstitial accumulation of fluid and inflammatory cells-but the underlying mechanism is unknown. Acute
The eicosanoid response to high dose UVR exposure of individuals prone and resistant to sunburn.
Anna Nicolaou,Mojgan Masoodi,Karl Gledhill,Ann Katarina Haylett,Anthony John Thody et al.
Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology null
Severely photosensitive psoriasis: a phenotypically defined patient subset.
Kirsty J Rutter,Rachel E B Watson,Lindsey F Cotterell,Thomas Brenn et al.
The Journal of Investigative Dermatology null
K M Skubitz et al.
Journal of leukocyte biology, 44(3), 158-165 (1988-09-01)
Neutrophil proteases are believed to play a role in the pathogenesis of a variety of human diseases. While many studies of proteases in models of disease have focused on elastase, neutrophils contain several proteases some of which share a high

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