CKT1MAG-97K
MILLIPLEX® Canine Kidney Toxicity Expanded Magnetic Bead Panel 1, CKT1MAG-97K
The analytes available for this multiplex kit are: Clusterin, Cystatin C, Kidney Injury Molecule-1 (KIM-1), IL-8, Lipocalin-2/NGAL, MCP-1, Osteopontin (OPN).
About This Item
Produits recommandés
Niveau de qualité
Espèces réactives
canine
Fabricant/nom de marque
Milliplex®
assay range
accuracy: 89-107%
sensitivity: 0.005-0.630 ng/mL
(All other analytes; MinDC +2SD)
sensitivity: 0.670 pg/mL
(KIM-1; MinDC +2SD)
standard curve range: 0.01-10 ng/mL
(Cystatin C)
standard curve range: 0.01-10 ng/mL
(Osteopontin)
standard curve range: 0.03-20 ng/mL
(Lipocalin-2/NGAL)
standard curve range: 0.07-50 ng/mL
(IL-8)
standard curve range: 0.07-50 ng/mL
(MCP-1)
standard curve range: 1.0-700 pg/mL
(KIM-1)
standard curve range: 1.4-1,000 ng/mL
(Clusterin)
Technique(s)
multiplexing: suitable
Méthode de détection
fluorometric (Luminex xMAP)
Conditions d'expédition
wet ice
Description générale
The MILLIPLEX® Canine Kidney Toxicity Expanded Panel 1 is to be used for the simultaneous quantification of the following 7 analytes in any combination in canine urine samples: Clusterin, Cystatin C, Kidney Injury Molecule-1 (KIM-1), IL-8, Lipocalin-2/NGAL, MCP-1, and Osteopontin (OPN). This kit uses a 96-well format, contains a lyophilized standard cocktail, two internal assay quality controls while can measure up to 38 samples in duplicate.
The Luminex® xMAP® platform uses a magnetic bead immunoassay format for ideal speed and sensitivity to quantitate multiple analytes simultaneously, dramatically improving productivity while conserving valuable sample volume.
Panel Type: Toxicity
Application
- Analytes: Clusterin, Cystatin C, Kidney Injury Molecule-1 (KIM-1), IL-8, Lipocalin-2/NGAL, MCP-1, Osteopontin (OPN)
- Recommended Sample Type: Canine urine
- Recommended Sample Dilution: 25 μL of 1:2 diluted urine for normal subjects; optimal dilutions for disease subjects should be determined
- Assay Run Time: Primary incubation of 2 hours, followed by a secondary incubation of 1 hour, both at room temperature (20-25°C)
- Research Category: Toxicology
Caractéristiques et avantages
Autres remarques
Informations légales
Mention d'avertissement
Danger
Mentions de danger
Classification des risques
Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2
Organes cibles
Respiratory Tract
Code de la classe de stockage
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
Certificats d'analyse (COA)
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Contenu apparenté
Novel kidney toxicity biomarkers expand options for acute nephrotoxicity detection. Multiplex assays measure multiple renal damage biomarkers in small sample volumes, minimizing time and costs. See how MILLIPLEX® multiplex kidney toxicity assays detected vancomycin-induced subacute nephrotoxicity in rat models.
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