ABE1008

Anti-Ligand-dependent nuclear receptor-interacting factor 1 Antibody

0.5 mg/mL, from rabbit

• Synonyme(s) : Ligand-dependent nuclear receptor-interacting factor 1, LRIF1, RIF1, C1orf103, Receptor-interacting factor 1
• Code UNSPSC : 12352203
• eCl@ss : 32160702
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Produit purifié par: affinity chromatography
• Espèces réactives: human, mouse
• Réactivité de l'espèce (prédite par homologie): primate (based on 100% sequence homology)
• Concentration: 0.5 mg/mL
• Technique(s): immunocytochemistry: suitable; western blot: suitable
• Numéro d'accès NCBI: NP_060842
• Numéro d'accès UniProt: Q5T3J3
• Conditions d'expédition: wet ice
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... LRIF1(55791)

Description

Description générale

Ligand-dependent nuclear receptor-interacting factor 1 (LRIF1), also known as RIF1, Receptor-interacting factor 1, and is encoded by the gene LRIF1/C1orf103/RIF1. The retinoic acid receptors (RARs) are ligand-dependent transcription factors that play critical roles in cell differentiation, embryonic development, and tumor suppression. RAR transcriptional activities are mediated by a growing family of nuclear receptor (NR) coregulators. Ligand-dependent nuclear receptor-interacting factor 1 (LRIF1) is such a coregulator. Ligand-dependent nuclear receptor-interacting factor 1 (LRIF1) is a repressor of ligand-induced transcriptional activity of retinoic receptor alpha. Ligand-dependent nuclear receptor-interacting factor 1 (LRIF1) is ubiquitously expressed in a wide variety of tissues and cells and localizes exclusively to the nucleus and specifically to the nuclear matrix.

Immunogène

Epitope: Near C-terminus

KLH-conjugated linear peptide corresponding to a region near the C-terminus of human Ligand-dependent nuclear receptor-interacting factor 1.

Application

Immunocytochemistry Analysis: A 1:100 dilution from a representative lot detected Ligand-dependent nuclear receptor-interacting factor 1 in HeLa, A431, HepG2, and NIH/3T3 cells.

Research Category
Epigenetics & Nuclear Function

Research Sub Category
Chromatin Biology

This Anti-Ligand-dependent nuclear receptor-interacting factor 1 Antibody is validated for use in western blotting & ICC for the detection of Ligand-dependent nuclear receptor-interacting factor 1.

Qualité

Evaluated by Western Blotting in SH-SY5Y cell lysate.

Western Blotting Analysis: A 1:2,000 dilution of this antibody detected Ligand-dependent nuclear receptor-interacting factor 1 in 10 µg of SH-SY5Y cell lysate.

Description de la cible

~100 kDa observed

Forme physique

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Stockage et stabilité

Stable for 1 year at 2-8°C from date of receipt.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable