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Autres documents

AB770

Sigma-Aldrich

Anti-TIMP-1 Antibody

Chemicon®, from rabbit

Synonyme(s) :

Tissue Inhibitor of Metalloproteinase-1

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

rabbit

Niveau de qualité

100

Forme d'anticorps

purified immunoglobulin

Type de produit anticorps

primary antibodies

Clone

polyclonal

Produit purifié par

affinity chromatography

Espèces réactives

bovine, rat, ferret, sheep, horse, rabbit

Fabricant/nom de marque

Chemicon®

Technique(s)

ELISA: suitable
immunohistochemistry: suitable
western blot: suitable

Numéro d'accès NCBI

NM_003254.2

Numéro d'accès UniProt

P01033

Conditions d'expédition

dry ice

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... TIMP1(7076)

Spécificité

Reacts with TIMP1. Does not react with any other human proteins tested so far. The antibody reacts with native and denatured TIMP1 and TIMP1 in and out of enzyme/inhibitor complex.

Immunogène

Full length purified human fibroblast tissue inhibitor of metalloproteinases {Clark, IM (1991) Matrix 11:76-85}.

Application

Anti-TIMP-1 Antibody detects level of TIMP-1 & has been published & validated for use in ELISA, WB, IH.
Research Category
Cell Structure
Research Sub Category
MMPs & TIMPs
Western Blotting at 5-10 μg/mL: recognizes a band of approximately 28-30kDa in reduced samples.

Immunohistochemistry: frozen and 4%PFA fixed paraffin sections: 5-20μg/mL enzymatic detection.



Optimal working dilutions must be determined by end user.

Liaison

Replaces: 04-1133

Forme physique

Purified immunoglobulin. Liquid in PBS containing 0.02% azide.

Stockage et stabilité

Maintain refrigerated at 2-8°C for up to three months from date of receipt. For extended storage, freeze in convenient undiluted aliquots at -20°C for up to twelve months from date of receipt. Avoid repeated freeze/thaw cycles.

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informations légales

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Renal connective tissue growth factor correlates with glomerular basement membrane thickness and prospective albuminuria in a non-human primate model of diabetes: possible predictive marker for incipient diabetic nephropathy.
Sally E Thomson,Susan V McLennan,Paul D Kirwan,Scott J Heffernan,Annemarie Hennessy et al.
Journal of Diabetes and Its Complications null
Polyclonal antibodies against human fibroblast collagenase and the design of an enzyme-linked immunosorbent assay to measure TIMP-collagenase complex.
Clark, I M, et al.
Matrix, 12, 108-115 (1992)
T A Plumpton et al.
Clinica chimica acta; international journal of clinical chemistry, 240(2), 137-154 (1995-09-15)
A panel of six monoclonal antibodies (MAbs) was raised against purified human fibroblast tissue inhibitor of metalloproteinase-1 (TIMP-1) and characterised. All possible antibody pairs were tested for their suitability as capture and revealing antibodies in a two-site enzyme-linked immunosorbent assay
Polyclonal and monoclonal antibodies against human tissue inhibitor of metalloproteinases (TIMP) and the design of an enzyme-linked immunosorbent assay to measure TIMP
Clark, I M, et al
Matrix, 11, 76-85 (1991)
Monoclonal antibodies against human fibroblast collagenase and the design of an enzyme-linked immunosorbent assay to measure total collagenase
Clark, I M, et al
Matrix, 12, 475-480 (1992)
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