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Principaux documents

AB5848

Sigma-Aldrich

Anti-GABA B Receptor R2 Antibody, a.a. 42-54 rat

Chemicon®, from rabbit

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

rabbit

Niveau de qualité

Forme d'anticorps

purified immunoglobulin

Type de produit anticorps

primary antibodies

Clone

polyclonal

Espèces réactives

human, rat

Fabricant/nom de marque

Chemicon®

Technique(s)

western blot: suitable

Numéro d'accès NCBI

Numéro d'accès UniProt

Conditions d'expédition

dry ice

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... GABBR2(9568)

Description générale

The inhibitory neurotransmitter, GABA, acts through two ligand-gated channels, GABA(A) and GABA© receptors and GABA(B), the latter of which acts through a G protein mechanism. GABA(B)R2 is one of the two G-protein coupled receptors for GABA(B) that acts as a heteromeric assembly with GABA(B)R1.

Spécificité

GABAB Receptor R2 subunit, N-terminus. No reactivity with GABABR1 has been detected.

Immunogène

Epitope: a.a. 42-54 rat
peptide residues 42-54 of the rat 105 kDa GABA(b)R2 protein

Application

Immunoblotting: 1:500-1:1,000. Membrane preparations with proteinase inhibitors are recommended. Whole rat brain membrane preparations. The antibody detects a ~105kDa band under standard western conditions. The immunogen used is 100% conserved in human by sequence analysis; other species have not been examined for reactivity or homology.

Optimal working dilutions must be determined by end user.
Research Category
Neuroscience
Research Sub Category
Neurotransmitters & Receptors
This Anti-GABA B Receptor R2 Antibody, a.a. 42-54 rat is validated for use in WB for the detection of GABA B Receptor R2.

Forme physique

Format: Purified
Purified immunoglobulin. Liquid. Buffer = PBS containing 0.02% sodium azide.

Stockage et stabilité

Maintain frozen at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informations légales

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Differential trafficking of AMPA and NMDA receptors during long-term potentiation in awake adult animals.
Williams, JM; Guevremont, D; Mason-Parker, SE; Luxmanan, C; Tate, WP; Abraham, WC
The Journal of Neuroscience null
Distribution and function of GABAB receptors in spider peripheral mechanosensilla.
Panek, I; Meisner, S; Torkkeli, PH
Journal of Neurophysiology null
Immunohistochemical and immunoblot analysis of gamma-aminobutyric acid B receptor in the prefrontal cortex of subjects with schizophrenia and bipolar disorder.
Masanori Ishikawa, Katsuyoshi Mizukami, Masahiko Iwakiri, Takashi Asada
Neuroscience Letters null
Functional expression of the GABAB receptor in human airway smooth muscle.
Osawa, Y; Xu, D; Sternberg, D; Sonett, JR; D'Armiento, J; Panettieri, RA; Emala, CW
American Journal of Physiology. Lung Cellular and Molecular Physiology null

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