AB3500P
Anti-Anion Exchanger 1 Antibody
Chemicon®, from rabbit
Synonyme(s) :
AE1
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About This Item
Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41
Produits recommandés
Source biologique
rabbit
Niveau de qualité
Forme d'anticorps
affinity purified immunoglobulin
Type de produit anticorps
primary antibodies
Clone
polyclonal
Produit purifié par
affinity chromatography
Espèces réactives
rat
Fabricant/nom de marque
Chemicon®
Technique(s)
ELISA: suitable
western blot: suitable
Numéro d'accès NCBI
Numéro d'accès UniProt
Conditions d'expédition
dry ice
Modification post-traductionnelle de la cible
unmodified
Informations sur le gène
rat ... Slc4A1(24779)
Spécificité
Recognizes rat Anion Exchanger 1 (AE1). The immunogen shows no significant sequence homology with other AE or other proteins.
SPECIES REACTIVITIES: The immunogen sequence is 90% conserved in mouse, 75% in human and 70% in bovine. Reactivity with other species has not been confirmed.
SPECIES REACTIVITIES: The immunogen sequence is 90% conserved in mouse, 75% in human and 70% in bovine. Reactivity with other species has not been confirmed.
Immunogène
A 20 amino acid peptide sequence near the N-terminus of rat AE1 (Kudrycki et al. 1989; Kopito et al. 1985; Raida et al. 1989; Lux et al. 1989; Tanner et al. 1988).
Application
Anti-Anion Exchanger 1 Antibody detects level of Anion Exchanger 1 & has been published & validated for use in ELISA & WB.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Ion Channels & Transporters
Ion Channels & Transporters
Western blot: 1-10 μg/mL using ECL. AE1 has a molecular weight of approximately 90-100 kDa. It aggregates easily forming dimers and multimers. It may also be proteolytically processed to smaller fragments of 60, 40 and 20 kDa.
ELISA: 1-10 μg/mL using 1 μg/mL control peptide per well.
Optimal working dilutions must be determined by the end user.
ELISA: 1-10 μg/mL using 1 μg/mL control peptide per well.
Optimal working dilutions must be determined by the end user.
Forme physique
Affinity purified immunoglobulin. Liquid in Liquid in PBS with 0.1% BSA.
Stockage et stabilité
Maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.
Autres remarques
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Informations légales
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Clause de non-responsabilité
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Code de la classe de stockage
12 - Non Combustible Liquids
Classe de danger pour l'eau (WGK)
WGK 2
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Certificats d'analyse (COA)
Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".
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SLC4A11 prevents osmotic imbalance leading to corneal endothelial dystrophy, deafness, and polyuria.
Nicole Gröger et al.
The Journal of biological chemistry, 285(19), 14467-14474 (2010-02-27)
Maintenance of ion concentration gradients is essential for the function of many organs, including the kidney, the cornea, and the inner ear. Ion concentrations and fluid content in the cornea are regulated by endothelial cells that separate the collagenous avascular
Nicole Gröger et al.
Human molecular genetics, 21(5), 1025-1036 (2011-11-16)
The human SLC4A5 gene has been identified as a hypertension susceptibility gene based on the association of single nucleotide polymorphisms with blood pressure (BP) levels and hypertension status. The biochemical basis of this association is unknown particularly since no single
Sekiya Shibazaki et al.
Human molecular genetics, 17(11), 1505-1516 (2008-02-12)
Polycystic kidney disease (ADPKD) results from failure of the kidney to properly maintain three-dimensional structure after loss of either polycystin-1 or -2. Mice with kidney selective inactivation of Pkd1 during embryogenesis develop profound renal cystic disease and die from renal
Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..
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