AB10514P

Anti-Serotonin Transporter Antibody

1 mg/mL, from rabbit

• Synonyme(s) : solute carrier family 6 (neurotransmitter transporter, serotonin), member 4, sodium-dependent serotonin transporter, serotonin transporter, Solute carrier family 6 member 4, Na+/Cl- dependent serotonin transporter, 5HT transporter, 5-hydroxytryptamine tr
• Code UNSPSC : 12352203
• eCl@ss : 32160702
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Produit purifié par: affinity chromatography
• Réactivité de l'espèce (prédite par homologie): sheep (100% homology), rat (100% homology), bovine (100% homology), monkey (100% homology), human (100% homology), horse (100% homology), mouse (100% homology), chimpanzee (100% homology)
• Concentration: 1 mg/mL
• Technique(s): western blot: suitable
• Numéro d'accès UniProt: P31645
• Conditions d'expédition: wet ice
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... HTT(3064)

Description

Description générale

This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma.

Spécificité

Other species have not been tested.

The antibody reacts with the 70 kDa serotonin transporter protein.

Immunogène

Epitope: Center region

This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human serotonin transporter.

Application

Research Category
Neuroscience

Research Sub Category
Ion Channels & Transporters

This Anti-Serotonin Transporter Antibody is validated for use in WB for the detection of Serotonin Transporter.

Qualité

Western Blot Analysis: 1:1000 dilution of this antibody detected serotonin transporter on human lung lysate.

Description de la cible

70 kDa

Liaison

Replaces: AB1594P

Forme physique

Antigen Affinity Purified

Purified in 0.1M Tris-Glycine (pH7.4) 150mM NaCl with 0.05% NaN3.

Stockage et stabilité

Store at 2-8°C for 1 year from date of receipt.

Remarque sur l'analyse

Control
Western Blot : Human lung lysate.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable