8.52112

Fmoc-Lys(Me₃Cl)-OH

Novabiochem^®

• Synonyme(s) : Fmoc-Lys(Me₃Cl)-OH, N-α-Fmoc-N-ε-trimethyl-N-L-lysine · chloride
• Formule empirique (notation de Hill): C₂₄H₃₁ClN₂O₄
• Numéro CAS: 201004-29-7
• Poids moléculaire : 446.97
• Code UNSPSC : 12352209
• Nomenclature NACRES : NA.22

Propriétés

• Niveau de qualité: 200
• Gamme de produits: Novabiochem^®
• Pureté: ≥95% (TLC); ≥95.0% (HPLC)
• Forme: powder
• Capacité de réaction: reaction type: Fmoc solid-phase peptide synthesis
• Fabricant/nom de marque: Novabiochem^®
• Application(s): peptide synthesis
• Groupe fonctionnel: amine
• Température de stockage: 2-8°C
• InChI: 1S/C24H30N2O4.ClH/c1-26(2,3)15-9-8-14-22(23(27)28)25-24(29)30-16-21-19-12-6-4-10-17(19)18-11-5-7-13-20(18)21;/h4-7,10-13,21-22H,8-9,14-16H2,1-3H3,(H-,25,27,28,29);1H/t22-;/m0./s1
• Clé InChI: XUJRNPVABVHOAJ-FTBISJDPSA-N

Description

Description générale

A novel derivative for the introduction of trimethyl-lysine during Fmoc SPPS. Ref ^[1] contains methods and protocols for the synthesis of arrays of histone-related peptides containing methylated arginine and lysine-residues.


Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Overcoming Aggregation in Fmoc SPPS

Literature references

^[1] S. Rothbart, et al. (2012) Methods Enzymol., 512, 107.

Liaison

Replaces: 04-12-1270

Remarque sur l'analyse

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Purity (TLC(CMA1)): ≥ 95 %
Assay (HPLC, area%): ≥ 95.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
LC/MS: passes test

To see the solvent systems used for TLC of Novabiochem^® products please click here.

Informations légales

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable