8.52040

Fmoc-Lys(Tfa)-OH

Novabiochem^®

• Synonyme(s) : Fmoc-Lys(Tfa)-OH, N-α-Fmoc-N-ε-trifluoroacetyl-L-lysine
• Formule empirique (notation de Hill): C₂₃H₂₃F₃N₂O₅
• Numéro CAS: 76265-69-5
• Poids moléculaire : 464.43
• Numéro MDL: MFCD00153360
• Code UNSPSC : 12352209
• Nomenclature NACRES : NA.22

Propriétés

• Niveau de qualité: 200
• Gamme de produits: Novabiochem^®
• Pureté: ≥97% (TLC); ≥97.0% (HPLC); ≥97.0% (acidimetric)
• Forme: powder
• Capacité de réaction: reaction type: Fmoc solid-phase peptide synthesis
• Fabricant/nom de marque: Novabiochem^®
• Pf: 150-160 °C
• Application(s): peptide synthesis
• Groupe fonctionnel: amine
• Température de stockage: 2-30°C
• InChI: 1S/C23H23F3N2O5/c24-23(25,26)21(31)27-12-6-5-11-19(20(29)30)28-22(32)33-13-18-16-9-3-1-7-14(16)15-8-2-4-10-17(15)18/h1-4,7-10,18-19H,5-6,11-13H2,(H,27,31)(H,28,32)(H,29,30)/t19-/m0/s1
• Clé InChI: ZVLMWTPNDXNXSZ-IBGZPJMESA-N

Description

Description générale

Building block for introduction of lysine amino-acid residues bearing orthogonal side-chain protection. The trifluoroacetyl group can be selectively removed by aqueous basic hydrolysis ^[1,2].

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

Literature references

^[1] E. Atherton, et al. (1980) J. Chem. Soc., Chem. Commun., 970.
^[2] D. A. Stetsenko & M. J. Gait (2001) Bioconjugate Chem., 12, 576.

Liaison

Replaces: 04-12-1083

Remarque sur l'analyse

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.5 % (a/a)
Purity (TLC(011A)): ≥ 97 %
Purity (TLC(0811)): ≥ 97 %
Assay (HPLC, area%): ≥ 97.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): ≥ 97.0 %
Water (K. F.): ≤ 1.00 %

To see the solvent systems used for TLC of Novabiochem^® products please click here.

Informations légales

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable