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36-003

Sigma-Aldrich

Anti-phospho-MYPT1 (Thr850) Antibody

Upstate®, from rabbit

Synonyme(s) :

Anti-GUBS, Anti-M130, Anti-MBS, Anti-MYPT1

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

rabbit

Niveau de qualité

100

Forme d'anticorps

purified immunoglobulin

Type de produit anticorps

primary antibodies

Clone

polyclonal

Espèces réactives

chicken, rat, human, mouse

Fabricant/nom de marque

Upstate®

Technique(s)

western blot: suitable

Isotype

IgG

Numéro d'accès NCBI

NM_002480.1

Numéro d'accès UniProt

O14974

Conditions d'expédition

dry ice

Modification post-traductionnelle de la cible

phosphorylation (pThr850)

Informations sur le gène

human ... PPP1R12A(4659)

Spécificité

Recombinant truncated chicken MYPT1 phosphorylated on Thr850.

Immunogène

Peptide corresponding to amino acid residues 845-855 of chicken MYPT1; this sequence is identical to amino acids 848-858 of human MYPT1, with the phosphorylated Thr at position 853.

Application

Detect phospho-MYPT1 (Thr850) using this Anti-phospho-MYPT1 (Thr850) Antibody validated for use in WB.
Research Category
Signaling
Research Sub Category
Kinases & Phosphatases

Qualité

Routinely evaluated by immunoblot on phophorylated MYPT1 substrate

Description de la cible

80 kDa

Forme physique

Format: Purified
Protein A Purified rabbit IgG in a solution of 30% glycerol, 0.07M Tris-glycine, pH 7.4, 0.135M NaCl, and 0.035% sodium azide as a preservative.
Protein A purified

Stockage et stabilité

Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Remarque sur l'analyse

Control
MYPT1 substrate phosphorylated by ROKa/ROCK-II

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informations légales

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Enhanced Ca2+-dependent activation of phosphoinositide 3-kinase class II? isoform-Rho axis in blood vessels of spontaneously hypertensive rats.
Seok, YM; Azam, MA; Okamoto, Y; Sato, A; Yoshioka, K; Maeda, M; Kim, I; Takuwa, Y
Hypertension null
Comparison of contractile mechanisms of sphingosylphosphorylcholine and sphingosine-1-phosphate in rabbit coronary artery.
Soo-Kyoung Choi,Duck-Sun Ahn,Young-Ho Lee
Cardiovascular Research null
Mechanically induced osteogenic differentiation--the role of RhoA, ROCKII and cytoskeletal dynamics.
Arnsdorf, EJ; Tummala, P; Kwon, RY; Jacobs, CR
Journal of Cell Science null
Substrate specificity and inhibitors of LRRK2, a protein kinase mutated in Parkinson's disease.
Nichols, RJ; Dzamko, N; Hutti, JE; Cantley, LC; Deak, M; Moran, J; Bamborough, P; Reith et al.
The Biochemical Journal null
An extract from brown rice inhibits signal transduction of angiotensin iI in vascular smooth Muscle cells.
Utsunomiya H, Takaguri A, Bourne AM, Elliott KJ, Akazawa S, Okuno Y, Kono R, Eguchi S
American Journal of Hypertension null
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