1.00090

Adipic acid

EMPROVE^® ESSENTIAL, Ph. Eur., NF

• Synonyme(s) : Adipic acid, Hexanedioic acid
• Formule empirique (notation de Hill): C₆H₁₀O₄
• Numéro CAS: 124-04-9
• Poids moléculaire : 146.14
• Numéro MDL: MFCD00004420
• Code UNSPSC : 12352106
• Numéro E: E355
• Numéro de classement CE : 204-673-3

Propriétés

• Agence: NF; Ph. Eur.
• Niveau de qualité: 500
• Conformité réglementaire: FCC
• Pression de vapeur: 0.097 hPa ( 18.5 °C)
• Description: EMPROVE^® ESSENTIAL Ph Eur,NF,FCC,E 355
• Gamme de produits: EMPROVE^® ESSENTIAL
• Forme: solid
• Température d'inflammation spontanée: 405 °C
• Puissance: 5700 mg/kg LD₅₀, oral (Rat); >7940 mg/kg LD₅₀, skin (Rabbit)
• Technique(s): API processing | cocrystal formation: suitable; API processing | salt formation: suitable
• pH: 2.7 (25 °C, 23 g/L in H₂O)
• Pf: 150.9 °C
• Température de transition: flash point 196 °C
• Solubilité: 15 g/L
• Densité: 1.36 g/cm³ at 25 °C
• Application(s): liquid formulation; pharmaceutical; solid formulation
• Température de stockage: 15-25°C
• InChI: 1S/C6H10O4/c7-5(8)3-1-2-4-6(9)10/h1-4H2,(H,7,8)(H,9,10)
• Clé InChI: WNLRTRBMVRJNCN-UHFFFAOYSA-N

Description

Description générale

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our EMPROVE^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Adipic acid is typically used as a pH modifier in pharmaceutical applications.

Informations légales

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Pictogrammes: GHS05
• Mention d'avertissement: Danger
• Mentions de danger: H318
• Conseils de prudence: P280 - P305 + P351 + P338
• Classification des risques: Eye Dam. 1
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): 384.8 °F - closed cup
• Point d'éclair (°C): 196 °C - closed cup