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Merck
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Key Documents

07-228

Sigma-Aldrich

Anti-TACC2 Antibody

Upstate®, from rabbit

Synonyme(s) :

transforming, acidic coiled-coil containing protein 2

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

rabbit

Niveau de qualité

100

Forme d'anticorps

affinity isolated antibody

Type de produit anticorps

primary antibodies

Clone

polyclonal

Produit purifié par

affinity chromatography

Espèces réactives

human, mouse

Réactivité de l'espèce (prédite par homologie)

rat (based on 100% sequence homology)

Fabricant/nom de marque

Upstate®

Technique(s)

western blot: suitable

Numéro d'accès NCBI

NP_996738

Numéro d'accès UniProt

Q9JJG0

Conditions d'expédition

wet ice

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... TACC2(10579)

Description générale

TACC2, also known as transforming acidic coiled-coil-containing protein 2, belongs to the transforming acidic coiled-coil-containing (TACC) protein family. This group of proteins is defined by its highly conserved coiled-coil domain. This domain is necessary for the assignment of the centrosome-spindle apparatus during cell cycling. There are three proteins belonging to the TACC family; TACC1, TACC2, and TACC3. TACC2 has been reported as playing a necessary role in cultured cell microtubule stabilization. It has also been shown that the binding of TACC2 by T antigen can cause chromosomal instability and mitotic defects (Tei, 2009). Research into the over expression of TACC2 strongly suggests a potential function as a tumor suppressor (Tei, 2009).

Immunogène

KLH-conjugated linear peptide corresponding to the mature chain of mouse TACC2.

Application

Anti-TACC2 Antibody is a Rabbit Polyclonal Antibody for detection of TACC2 also known as transforming acidic coiled-coil containing protein 2 & has been validated in WB.

Qualité

Evaluated by Western Blot in mouse testis tissue lysate.

Western Blot Analysis: 2 µg/mL of this antibody detected TACC2 on 10 µg of mouse testis tissue lysate.

Description de la cible

Observed molecular weight, 73 kDa
Note this protein can be highly modified and several isoforms exist.

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informations légales

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

T L Wong et al.
Journal of applied microbiology, 103(4), 803-810 (2007-09-28)
To survey the prevalence of Salmonella in imported and domestic pet chews for assessing their potential in introducing novel pathogenic and antimicrobial resistant Salmonella serotype clones into New Zealand, and as vehicles of salmonellosis in the domestic home environment. Three
T L Buhr et al.
Journal of applied microbiology, 115(2), 398-408 (2013-05-23)
To develop test methods and evaluate survival of Bacillus anthracis Ames, B. anthracis ∆Sterne and B. thuringiensis Al Hakam spores after exposure to PES-Solid (a solid source of peracetic acid), including PES-Solid formulations with bacteriostatic surfactants. Spores (≥ 7 logs)
TACC1-chTOG-Aurora A protein complex in breast cancer.
Conte, N; Delaval, B; Ginestier, C; Ferrand, A; Isnardon, D; Larroque, C; Prigent et al.
Oncogene null
Ken-ichi Takayama et al.
Molecular endocrinology (Baltimore, Md.), 26(5), 748-761 (2012-03-30)
Despite the existence of effective antiandrogen therapy for prostate cancer, the disease often progresses to castration-resistant states. Elucidation of the molecular mechanisms underlying the resistance for androgen deprivation in terms of the androgen receptor (AR)-regulated pathways is a requisite to
Molecular cloning, genomic structure and interactions of the putative breast tumor suppressor TACC2.
Brenda Lauffart, Omkaram Gangisetty, Ivan H Still
Genomics null
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