N-068

(±)-Normetanephrine-D₃ hydrochloride solution

100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant^®

• Formule empirique (notation de Hill): C₉H₁₀D₃NO₃·HCl
• Numéro CAS: 1085333-97-6
• Poids moléculaire : 222.68
• Numéro CE : 200-659-6
• Numéro MDL: MFCD17018958
• Code UNSPSC : 41116107
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: certified reference material
• Forme: liquid
• Caractéristiques: Snap-N-Spike^®/Snap-N-Shoot^®
• Conditionnement: ampule of 1 mL
• Fabricant/nom de marque: Cerilliant^®
• Concentration: 100 μg/mL in methanol (as free base)
• Technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• Application(s): clinical testing; clinical testing
• Format: single component solution
• Température de stockage: −70°C
• Chaîne SMILES: OC(C([2H])([2H])N)([2H])C1=CC(OC)=C(O)C=C1.Cl
• InChI: 1S/C9H13NO3.ClH/c1-13-9-4-6(8(12)5-10)2-3-7(9)11;/h2-4,8,11-12H,5,10H2,1H3;1H/i5D2,8D;
• Clé InChI: VKFPRGQZWKTEON-IJJJTAPTSA-N

Description

Description générale

Normetanephrine, a metabolite of norepinephrine, is a marker for catecholamine-secreting tumors such as pheochromocytoma. This internal standard is suitable for LC-MS/MS monitoring of normetanephrine levels in urine or plasma for diagnostic testing or endocrinology.

Application

• Reference standard for mass spectrometry: (±)-Normetanephrine-D₃ hydrochloride solution is widely used as a stable isotope-labeled standard in mass spectrometry for analyzing catecholamine metabolites. This application is essential for enhancing the accuracy of quantitative measurements in biomedical research (Zou et al., 2024).


• Research tool in neurotransmitter metabolism: The solution serves as an invaluable research tool in the study of neurotransmitter metabolism, particularly in the context of understanding catecholamine pathways in neurological disorders. Its application helps delineate the biochemical processes involving catecholamines, aiding in the development of therapeutic strategies (Jaafar et al., 2024).


• Analytical standard in biomedical research: As a deuterated form of normetanephrine, the hydrochloride solution is used extensively as an analytical standard in various biomedical assays, contributing significantly to the standardization and reproducibility of experimental results (Chen et al., 2024).

Informations légales

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Pictogrammes: GHS02,GHS06,GHS08
• Mention d'avertissement: Danger
• Mentions de danger: H225,H301 + H311 + H331,H370
• Conseils de prudence: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• Classification des risques: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Organes cibles: Eyes
• Code de la classe de stockage: 3 - Flammable liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): 49.5 °F - closed cup
• Point d'éclair (°C): 9.7 °C - closed cup