H-047

Hydrocodone-D₆ solution

100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• Formule empirique (notation de Hill): C₁₈H₁₅NO₃D₆
• Numéro CAS: 1007844-38-3
• Poids moléculaire : 305.40
• Numéro CE : 200-659-6
• Numéro MDL: MFCD01861538
• Code UNSPSC : 41116107
• ID de substance PubChem : 329815117
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: certified reference material
• Forme: liquid
• Caractéristiques: Snap-N-Spike^®/Snap-N-Shoot^®
• Conditionnement: ampule of 1 mL
• Fabricant/nom de marque: Cerilliant^®
• drug control: Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)
• Concentration: 100 μg/mL in methanol
• Technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• Application(s): forensics and toxicology
• Format: single component solution
• Température de stockage: −20°C
• Chaîne SMILES: [2H]C([2H])([2H])Oc1ccc2C[C@@H]3[C@@H]4CCC(=O)[C@@H]5Oc1c2[C@]45CCN3C([2H])([2H])[2H]
• InChI: 1S/C18H21NO3/c1-19-8-7-18-11-4-5-13(20)17(18)22-16-14(21-2)6-3-10(15(16)18)9-12(11)19/h3,6,11-12,17H,4-5,7-9H2,1-2H3/t11-,12+,17-,18-/m0/s1/i1D3,2D3
• Clé InChI: LLPOLZWFYMWNKH-CWCHNPBGSA-N

Description

Description générale

This certified Snap-N-Spike^® solution is suitable for quantitation of hydrocodone levels or isotope dilution methods by LC/MS or GC/MS for pain prescription monitoring, clinical toxicology, pharmaceutical research, or forensic analysis. Hydrocodone is an opiate drug used as an analgesic to treat pain and as an antitussive for coughing or related conditions. Also known as dihydrocodeinone, it is one of the most common recreationally-abused prescription drugs due to its widespread availability. Common street names include “hydros”, “dones”, “vics”, and “itchies”.

Application

• Quantitative plasma analysis for opiates: A robust gas chromatography-triple quadrupole mass spectrometry assay was developed for quantifying opiates in human blood samples, including hydrocodone. Hydrocodone-D₆ was utilized as an internal standard, enhancing the accuracy and reliability of drug monitoring in clinical toxicology (Saad et al., 2019).


• Advanced LC-MS/MS method for opioid analysis: A liquid chromatography-tandem mass spectrometry method was validated for the analysis of hydrocoDoneand its metabolites in human plasma. Hydrocodone-D₆ served as a critical internal standard, facilitating precise quantification and pharmacokinetic studies in pharmaceutical research (Valtier et al., 2013).

Informations légales

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Pictogrammes: GHS02,GHS06,GHS08
• Mention d'avertissement: Danger
• Mentions de danger: H225,H301 + H311 + H331,H370
• Conseils de prudence: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• Classification des risques: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Organes cibles: Eyes
• Code de la classe de stockage: 3 - Flammable liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): 49.5 °F - closed cup
• Point d'éclair (°C): 9.7 °C - closed cup