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Merck
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Principaux documents

G-001

Supelco

GHB sodium salt solution

1.0 mg/mL in methanol (as salt), ampule of 1 mL, certified reference material, Cerilliant®

Synonyme(s) :

4-Hydroxybutyric acid sodium salt solution

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About This Item

Formule empirique (notation de Hill):
C4H7NaO3
Numéro CAS:
Poids moléculaire :
126.09
Numéro CE :
Numéro MDL:
Code UNSPSC :
41116107
Nomenclature NACRES :
NA.24

Qualité

certified reference material

Niveau de qualité

Forme

liquid

Caractéristiques

Snap-N-Spike®/Snap-N-Shoot®

Conditionnement

ampule of 1 mL

Fabricant/nom de marque

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IIA (Portugal)

Concentration

1.0 mg/mL in methanol (as salt)

Technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

Application(s)

forensics and toxicology

Format

single component solution

Température de stockage

−20°C

Chaîne SMILES 

OCCCC([O-])=O.[Na+]

InChI

1S/C4H8O3/c5-3-1-2-4(6)7/h5H,1-3H2,(H,6,7)/p-1

Clé InChI

SJZRECIVHVDYJC-UHFFFAOYSA-M

Catégories apparentées

Description générale

GHB, or γ-hydroxybutyrate, is a central nervous system depressant sold under the brand name Xyrem® and used medically to treat narcolepsy, excessive daytime sleepiness and in rare circumstances, alcoholism. GHB is also used recreationally as an intoxicant and date rape drug. Its many street names include “GBH”, “Liquid X”, “G”, “Juice”, and “Mils”.

Application


  • GHB sodium salt in sleep disorder research: A study on nocturnal sodium oxybate, a form of GHB sodium salt, revealed an increase in the anterior cingulate cortex magnetic resonance glutamate signal upon awakening, suggesting its potential application in modulating brain function in sleep research (Dornbierer et al., 2023).

  • Investigation of GHB Na+ in alcohol-addiction treatment: Research focusing on the effect of the sodium salt of gamma-hydroxybutyrate (GHB) for alcohol-addiction treatment, it is effective in maintaining abstinence, with less craving for alcohol and lower rates of relapse (Frisoni et al., 2023).

  • Gamma-hydroxybutyrate sodium for in vitro biochemical assays: A detailed study on the pharmacokinetics and metabolism of gamma-hydroxybutyrate (GHB) in rats perturbed by alcohol, offers a model for in vitro studies examining GHB′s biochemical behavior and interaction with alcohol (Kim et al., 2023).

Informations légales

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
Xyrem is a registered trademark of JPI Commercial, LLC

Pictogrammes

FlameSkull and crossbonesHealth hazard

Mention d'avertissement

Danger

Classification des risques

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Organes cibles

Eyes

Code de la classe de stockage

3 - Flammable liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

49.5 °F - closed cup

Point d'éclair (°C)

9.7 °C - closed cup


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Certificats d'analyse (COA)

Lot/Batch Number

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Consulter la Bibliothèque de documents

Sodium oxybate: not authorised for fibromyalgia.
Prescrire international, 21(133), 290-290 (2013-02-02)
When true enough is not good enough.
Nature medicine, 19(1), 1-1 (2013-01-09)
Jon Berner
Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 9(1), 71-72 (2013-01-16)
Our case describes clinical features of two families defined by joint phenotypes: sodium oxybate intolerance and elevated serum acylcarnitines. Oxybate intolerance variably presents as either cervical dystonia or sleep-related eating disorder. Our objective is to identify biological markers which predict
γ-Hydroxybutyrate toxicity mimicking basilar artery stroke.
N S N Graham et al.
British journal of hospital medicine (London, England : 2005), 73(7), 412-413 (2012-08-10)
R W Freudenmann et al.
Fortschritte der Neurologie-Psychiatrie, 81(2), 88-94 (2013-02-16)
In emergency medicine and anesthaesiology liquid ecstasy (LE), the street name for GHB, GBL or 1,4-B, has become infamous for causing severe intoxications and withdrawal. In general psychiatry, however, it is little known. Therefore, we set out to gather data

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