700016P

cholesterol sulfate

Avanti Polar Lipids 700016P

• Synonyme(s) : cholesterol sulfonate; cholesteryl sulfate; sodium cholesteryl sulfate; cholesteryl sulphate
• Formule empirique (notation de Hill): C₂₇H₄₅NaO₄S
• Numéro CAS: 2864-50-8
• Poids moléculaire : 488.70
• Code UNSPSC : 12352211
• Nomenclature NACRES : NA.25

Propriétés

• Description: cholesterol 3-sulfate (sodium salt)
• Pureté: >99% (TLC)
• Forme: powder
• Conditionnement: pkg of 1 × 1 g (700016P-1g); pkg of 1 × 25 mg (700016P-25mg); pkg of 1 × 500 mg (700016P-500mg)
• Fabricant/nom de marque: Avanti Polar Lipids 700016P
• Conditions d'expédition: dry ice
• Température de stockage: −20°C
• InChI: 1S/C27H46O4S.Na/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(31-32(28,29)30)13-15-26(20,4)25(22)14-16-27(23,24)5;/h9,18-19,21-25H,6-8,10-17H2,1-5H3,(H,28,29,30);/q;+1/p-1/t19-,21+,22+,23-,24+,25+,26+,27-;/m1./s1
• Clé InChI: LMPVQXVJTZWENW-KPNWGBFJSA-M

Description

Description générale

Cholesterol sulfate is synthesized by the sulfoconjugation of cholesterol in the presence of enzyme cholesterol sulfotransferase. It is present in brain, lungs, hair and skin tissues as well as cells including erythrocytes, platelets and spermatozoa.

Application

Cholesterol sulfate has been used in micelle preparation and in surface plasmon resonance (SPR) studies.

Actions biochimiques/physiologiques

Cholesterol sulfate is associated with atherosclerotic lesions and serves as a substrate for platelet adhesion. It stabilizes the spermatozoa membranes and erythrocytes. Cholesterol sulfate is involved in the keratinocyte differentiation and its levels are elevated in recessive X-linked ichthyosis. It serves as a ligand for retinoic acid-related orphan receptor α (RORα). Cholesterol sulfate regulates glucose metabolism and is a potential target for metabolic disorders. It is also a potential marker for human uterine cervical carcinoma tissue and prostate carcinoma.

Conditionnement

20 mL Clear Glass Screw Cap Vial (700016P-1g)

20 mL Clear Glass Screw Cap Vial (700016P-500mg)

5 mL Amber Glass Screw Cap Vial (700016P-25mg)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable