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W247804

Sigma-Aldrich

Farnesol

mixture of isomers, ≥95%, stabilized, FG

Synonyme(s) :

3,7,11-Trimethyl-2,6,10-dodecatrien-1-ol

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About This Item

Formule linéaire :
(CH3)2C=CHCH2CH2C(CH3)=CHCH2CH2C(CH3)=CHCH2OH
Numéro CAS:
4602-84-0
Poids moléculaire :
222.37
Numéro FEMA:
2478
Numéro Beilstein :
1763926
Numéro CE :
225-004-1
Conseil de l'Europe Nº :
78
Numéro MDL:
MFCD00002918
Code UNSPSC :
12164502
ID de substance PubChem :
24901122
Numéro Flavis :
2.029
Nomenclature NACRES :
NA.21

Source biologique

synthetic

Niveau de qualité

400

Qualité

FG
Halal
Kosher

Conformité réglementaire

EU Regulation 1334/2008 & 178/2002
FDA 21 CFR 117
FDA 21 CFR 172.515

Pureté

≥95%

Contient

α-tocopherol (synthetic stabilizer)

Peut contenir

≤50 ppm hexane

Indice de réfraction

n20/D 1.489 (lit.)

Point d'ébullition

149 °C/4 mmHg (lit.)

Densité

0.886 g/mL at 20 °C (lit.)

Application(s)

flavors and fragrances

Documentation

see Safety & Documentation for available documents

Allergène alimentaire

no known allergens

Propriétés organoleptiques

fresh; floral; sweet

Chaîne SMILES 

C/C(CC/C=C(C)/CCC=C(C)C)=C\CO

InChI

1S/C15H26O/c1-13(2)7-5-8-14(3)9-6-10-15(4)11-12-16/h7,9,11,16H,5-6,8,10,12H2,1-4H3/b14-9+,15-11+

Clé InChI

CRDAMVZIKSXKFV-YFVJMOTDSA-N

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Application


  • Farnesol repurposing for prevention and treatment of Acinetobacter baumannii biofilms.: This article explores the efficacy of repurposing farnesol for preventing and treating biofilms caused by Acinetobacter baumannii, highlighting its potential as an antibacterial agent (Tan et al., 2024).

  • Methyl-Jasmonate Functions as a Molecular Switch Promoting Cross-Talk between Pathways for the Biosynthesis of Isoprenoid Backbones Used to Modify Proteins in Plants.: This study investigates the role of methyl-jasmonate in regulating the biosynthesis of isoprenoid backbones, which are crucial for post-translational modification of proteins in plants and may involve farnesol as an intermediate or by-product (Chevalier et al., 2024).

  • Repurposing Farnesol for Combating Drug-Resistant and Persistent Single and Polymicrobial Biofilms.: This article discusses the potential of repurposing farnesol to combat drug-resistant and persistent biofilms, demonstrating its utility in enhancing antibiotic efficacy and addressing antimicrobial resistance (Tan et al., 2024).

Actions biochimiques/physiologiques

Taste at 10 ppm

Autres remarques

Natural occurrence: Apricot, orange peel and oil, grapefruit juice, cloves, ginger thyme beef, whiskey basil, papaya, anise seed and balsam of Peru.

Pictogrammes

Exclamation markEnvironment
GHS07,GHS09

Mention d'avertissement

Warning

Mentions de danger

H315,H317,H410

Classification des risques

Aquatic Acute 1 - Aquatic Chronic 1 - Skin Irrit. 2 - Skin Sens. 1

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

311.0 °F - closed cup

Point d'éclair (°C)

155 °C - closed cup

Équipement de protection individuelle

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

Najla Nasr et al.
Blood, 120(4), 778-788 (2012-06-09)
Macrophages are key target cells for HIV-1. HIV-1(BaL) induced a subset of interferon-stimulated genes in monocyte-derived macrophages (MDMs), which differed from that in monocyte-derived dendritic cells and CD4 T cells, without inducing any interferons. Inhibition of type I interferon induction
Rossana de Aguiar Cordeiro et al.
Veterinary microbiology, 159(3-4), 375-380 (2012-05-15)
Farnesol is a sesquiterpene alcohol that modulates cell-to-cell communication in Candida albicans. In recent years, several studies have shown that this molecule presents inhibitory effects against non-albicans Candida species, Paracoccidioides brasiliensis and bacteria. The present study aimed at determining the
Efrat Mashiach-Farkash et al.
Oncotarget, 3(6), 629-639 (2012-07-11)
Neurofibromin regulates cell motility via three distinct GTPase pathways acting through two different domains, the Ras GTPase-activating protein-related domain (GRD) and the pre-GRD domain. First, the GRD domain inhibits Ras-dependent changes in cell motility through the mitogen activated protein cascade.
N Charette et al.
Cell death & disease, 4, e471-e471 (2013-01-26)
Ras activation is a frequent event in human hepatocarcinoma that may contribute to resistance towards apoptosis. Salirasib is a ras and mTOR inhibitor that induces a pro-apoptotic phenotype in human hepatocarcinoma cell lines. In this work, we evaluate whether salirasib
E Fayard et al.
Current opinion in lipidology, 12(2), 113-120 (2001-03-27)
Cholesterol and bile acid metabolism is tightly controlled by nuclear receptors. The liver X receptor, an oxysterol-activated nuclear receptor, limits cholesterol accumulation in the body both by stimulating reverse cholesterol transport and by inhibiting intestinal cholesterol absorption. The liver X
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