NCXGSNR15010S
Gold Nanoshells
150 nm, for Conjugation, Bioready, Dried, NHS, Small Reaction Kit (with 10 Spin Filters), kit of 10 units
Synonyme(s) :
Gold Nanoshells
About This Item
Produits recommandés
Forme
nanoshells
Conditionnement
kit of 10 units
Taille des particules
150 nm
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Description générale
Application
Our BioReady materials are engineered for reliable conjugation to antibodies, proteins, peptides, and other biomolecules and are ideal for lateral flow (immunochromatographic assays) and other diagnostics related applications.
The BioReady spherical gold nanoshells are made up of silica core and gold shell and are available with carboxyl, NHS, and streptavidin surface functional groups. These novel gold nanoshells are well suited for lateral flow assay applications. The gold nanoshells show strong absorbance and exhibit greater per-particle signal and, compared to the conventional 40 nm gold nanoparticles, these could enhance the assay sensitivity by 20 fold. Gold surface in these nanoshells is promising as the substitution of gold nanoshells in existing gold nanoparticles-based assays should be easy. The gold nanoshells offer a high contrast blue/gray stripe line (compared to red or pink stripe from 40 nm gold).
Gold nanoshells with carboxyl surface can be used for robust covalent conjugation. This allows for greater stability, sensitivity, reproducibility, and control over particle antibody loading (often requires less antibody compared to passive adsorption). Our covalently-bound streptavidin conjugated gold nanoshells allow easy binding with biotin.
The BioReady conjugation kits contain dried gold nanoshells with NHS-activated carboxyl surface. With pre-functionalized nanoshells with EDC/NHS surface, these are well suited for rapid antibody screening.
The small reaction NHS kits contain 50 μL of 20 OD gold in each unit whereas the large reaction kits contain 500 μL of 20 OD gold in each unit.
Stockage et stabilité
NHS Dried material: Store at -20C. Avoid freeze-thaw cycles. Note: NHS material is shipped ambient but should be placed in the freezer upon arrival. Sonicate to resuspend. Store additional kit components according to their labels.
Informations légales
Mention d'avertissement
Danger
Mentions de danger
Conseils de prudence
Classification des risques
Aquatic Chronic 3 - Carc. 2 - Eye Dam. 1 - Skin Sens. 1
Code de la classe de stockage
10 - Combustible liquids
Certificats d'analyse (COA)
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Articles
Drs. Fernandes and Baptista explore the synthesis and functionalization of gold nanoparticles and their use in molecular diagnostics, focusing on lateral flow assays. They further discuss the regulations and standards of these materials, as well as the future outlook and challenges.
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