900258

Isopropoxy(phenyl)silane

• Synonyme(s) : RubenSilane
• Formule empirique (notation de Hill): C₉H₁₄OSi
• Numéro CAS: 910037-63-7
• Poids moléculaire : 166.29
• Numéro MDL: MFCD31707672
• Code UNSPSC : 12352005
• Nomenclature NACRES : NA.22

Propriétés

• Forme: liquid
• Niveau de qualité: 100
• Pertinence de la réaction: reagent type: reductant; reaction type: Reductions
• Indice de réfraction: n/D 1.4799
• Densité: 0.926 g/mL
• Température de stockage: 2-8°C
• Chaîne SMILES: [SiH2](OC(C)C)c1ccccc1
• InChI: 1S/C9H14OSi/c1-8(2)10-11-9-6-4-3-5-7-9/h3-8H,11H2,1-2H3
• Clé InChI: XYMAHMLQCLMTDN-UHFFFAOYSA-N

Description

Description générale

Isopropoxy(phenyl)silane is used as a stoichiometric reductant that allows for a significant decrease in catalyst loading, lower reaction temperatures, a wide range of functional group tolerance, and more diverse solvents in metal-catalyzed Mukaiyama hydrofunctionalizations.

Application

Isopropoxy(phenyl)silane can be used as a hydride source for alkene hydrofunctionalization reactions in the presence of metal catalysts, particularly under aprotic, nonalcoholic conditions. This reagent is considered as one of the most efficient stoichiometric reductants than phenylsilane because of its ability to exclude alcohol solvent from a series of catalytic reactions. When utilized, it allows the researcher to significantly decrease catalyst loadings, lower reaction temperatures, and employ more diverse solvents in iron- and manganese-catalyzed Mukaiyama hydrofunctionalizations.
It can be used as a reagent in:

• The hydrogenation of olefins
• Branch-selective olefin cross-coupling reactions
• Markovnikov alkene hydration/amination reactions

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 3