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767344

Sigma-Aldrich

Poly(D,L-lactide)

average Mn 20,000 (NMR), PDI ≤1.3

Synonyme(s) :

PDLA, PLA, polyDL-lactide

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About This Item

Code UNSPSC :
12162002
Nomenclature NACRES :
NA.23

Forme

crystals

Niveau de qualité

100

Poids mol.

average Mn 20,000 (NMR)

Intervalle de dégradation

<6 months

Pf

320-350 °C

PDI

≤1.3

Température de stockage

2-8°C

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Catégories apparentées

Application

Used in Drug Delivery including coating nanoparticles. Can be end-group functionalizated or used as a macroinitiator/block precursor.

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H319

Classification des risques

Eye Irrit. 2

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Faites votre choix parmi les versions les plus récentes :

Certificats d'analyse (COA)

Lot/Batch Number
MKCL3830
MKCF1864
MKBX2656V
MKBR4541V
MKBL8301V

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Synthesis of Shape Amphiphiles Based on Functional Polyhedral Oligomeric Silsesquioxane End-Capped Poly(L-Lactide) with Diverse Head Surface Chemistry
Zhang W B, et al.
Macromolecules, 44(8), 2589-2596 (2011)
Poly(lactide)-block-Poly(HEMA) Block Copolymers: An Orthogonal One-Pot Combination of ROP and ATRP, Using a Bifunctional Initiator
Wolf F F, et al.
Macromolecules, 42(15), 5622-5628 (2009)
Preparation of Protein-Loaded Poly(L-Lactide) Microspheres by Solution-Enhanced Dispersion by Supercritical CO2
Chen A Z, et al.
Journal of Biomimetics, Biomaterials, and Tissue Engineering, 11, 93-100 (2011)

Articles

Electrospun Nanofibers for Drug Delivery Systems

Local delivery of bioactive molecules using an implantable device can decrease the amount of drug dose required as well as non-target site toxicities compared to oral or systemic drug administration.

Fabrication of Drug-loaded Microparticles Using Hydrogel Technology and Recent Innovation in Automation

Microparticle drug delivery systems have been extensively researched and applied to a wide variety of pharmaceutical and medical applications due to a number of advantages including injectability, local applicability to target tissues and sites, and controlled drug delivery over a given time period.

Poly(Glycerol Sebacate) in Tissue Engineering and Regenerative Medicine

The world of commercial biomaterials has stagnated over the past 30 years as few materials have successfully transitioned from the bench to clinical use. Synthetic aliphatic polyesters have continued to dominate the field of resorbable biomaterials due to their long history and track record of approval with the U.S. Food and Drug Administration (FDA).

Biodegradable Polyester Based Nanoparticle Formation by Miniemulsion Technique

Aliphatic polyesters such as polylactide, poly(lactide-co-glycolide) and polycaprolactone, as well as their copolymers, represent a diverse family of synthetic biodegradable polymers that have been widely explored for medical uses and are commercially available.

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