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725358

Sigma-Aldrich

Iron oxide(II,III), magnetic nanoparticles solution

10 nm avg. part. size, 5 mg/mL in H2O

Synonyme(s) :

Magnetic iron oxide nanocrystals, Magnetite, Superparamagnetic iron oxide nanoparticles

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About This Item

Formule empirique (notation de Hill):
Fe3O4
Numéro CAS:
Poids moléculaire :
231.53
Numéro MDL:
Code UNSPSC :
12352302
ID de substance PubChem :
Nomenclature NACRES :
NA.23

Forme

dispersion
nanoparticles

Niveau de qualité

Concentration

5 mg/mL in H2O

Magnétisation

>45 emu/g, at 4500Oe

Taille moy. des particules

10 nm

Taille des particules

9-11 nm (TEM)

Densité

1.00 g/mL at 25 °C

Chaîne SMILES 

O=[Fe].O=[Fe]O[Fe]=O

InChI

1S/3Fe.4O

Clé InChI

SZVJSHCCFOBDDC-UHFFFAOYSA-N

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Description générale

Concentration 5mg/ml includes total weight nanocrystals plus ligands.

Application



  • Optical resolution of ephedrine: A study explored the optical resolution of racemic ephedrine using various derivatives of tartaric acid, presenting a method that could refine the production of pharmaceutical-grade ephedrine hydrochloride (Bánhegyi et al., 2022).


  • Stereoselective forensic analysis: Supercritical fluid chromatography coupled with tandem mass spectrometry was used to perform a stereoselective analysis of ephedrine and its isomers in seized methamphetamine samples, offering insights into forensic applications of ephedrine hydrochloride (Segawa et al., 2021).


  • Chiral analysis of stimulants: A chiral high-performance liquid chromatography-tandem mass spectrometry method was applied to determine amphetamine-type stimulants, including ephedrine, in forensic samples, providing a tool for the precise separation and identification of chiral drugs (Schwelm et al., 2020).


Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

nwg

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


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Jens Baumgartner et al.
Nature materials, 12(4), 310-314 (2013-02-05)
The formation of crystalline materials from solution is usually described by the nucleation and growth theory, where atoms or molecules are assumed to assemble directly from solution. For numerous systems, the formation of the thermodynamically stable crystalline phase is additionally
Marina I Siponen et al.
Nature, 502(7473), 681-684 (2013-10-08)
Magnetotactic bacteria align along the Earth's magnetic field using an organelle called the magnetosome, a biomineralized magnetite (Fe(II)Fe(III)2O4) or greigite (Fe(II)Fe(III)2S4) crystal embedded in a lipid vesicle. Although the need for both iron(II) and iron(III) is clear, little is known
Maoquan Chu et al.
Biomaterials, 34(16), 4078-4088 (2013-03-08)
The photothermal effect of Fe3O4 magnetic nanoparticles is investigated for cancer therapy both in vitro and in vivo experiments. Heat is found to be rapidly generated by red and near-infrared (NIR) range laser irradiation of Fe3O4 nanoparticles with spherical, hexagonal and wire-like
A Aranda et al.
Toxicology in vitro : an international journal published in association with BIBRA, 27(2), 954-963 (2013-01-30)
No consensus exists on how to address possible toxicity of nanomaterials as they interfere with most in vitro screening tests based on colorimetric and fluorimetric probes such as the dichloro-dihydro-fluorescein diacetate (DCFH-DA) assay for detection of oxidative species. In the
Tsung-Ju Li et al.
Biomaterials, 34(32), 7873-7883 (2013-07-24)
We present an approach for synchronizing hyperthermia and thermal-responsive local drug release. The targeting probe has a magnetite nanocrystal (Fe₃O₄@PSMA) core and a polynucleotide shell that carries 5-fluorouracil (5-FU) and anti-human epidermal growth factor receptor 2 (anti-HER2) antibody for cancer

Articles

Currently, magnetic nanoparticles (MNPs) are attracting a lot of attention because of the possibility of many novel applications, especially in biomedical research.

A key challenge for nanomaterial safety assessment is the ability to handle the large number of newly engineered nanomaterials (ENMs), including developing cost-effective methods that can be used for hazard screening.

Professor Hui Mao explores the use of superparamagnetic iron oxide nanoparticles (INOPs) that offer an alternate contrast-enhancing mechanism.

Professor Yadong Yin (University of California Riverside, USA) examines both direct (thermal decomposition, solvothermal, hydrothermal) and indirect (templated) synthesis methods of magnetite nanocrystals and reviews in detail the landscape of these various synthetic methods for magnetite nanocrystal and their applications in magnetic assembly, magnetic hyperthermia, and Li-Ion batteries.

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