467464
Thianaphthene-2-carboxylic acid
98%
Synonyme(s) :
Benzo[b]thiophene-2-carboxylic acid
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About This Item
Formule empirique (notation de Hill):
C9H6O2S
Numéro CAS:
Poids moléculaire :
178.21
Numéro MDL:
Code UNSPSC :
12352100
ID de substance PubChem :
Nomenclature NACRES :
NA.22
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Niveau de qualité
Pureté
98%
Pf
241-244 °C (lit.)
Chaîne SMILES
OC(=O)c1cc2ccccc2s1
InChI
1S/C9H6O2S/c10-9(11)8-5-6-3-1-2-4-7(6)12-8/h1-5H,(H,10,11)
Clé InChI
DYSJMQABFPKAQM-UHFFFAOYSA-N
Description générale
Thianaphthene-2-carboxylic acid, a benzothiophene, is a heterocyclic sulfur compound. It undergoes degradation (23%) by employing a mixture of washed cells of Rhodococcus erythropolis DS-3 and Gordonia sp. C-6.
Application
Thianaphthene-2-carboxylic acid may be used for the fabrication of carboxylated conducting polymer/CNTs (carbon nanotubes) composites thin films.
Mention d'avertissement
Warning
Mentions de danger
Conseils de prudence
Classification des risques
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Organes cibles
Respiratory system
Code de la classe de stockage
11 - Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 3
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Équipement de protection individuelle
dust mask type N95 (US), Eyeshields, Gloves
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J C Robin et al.
Calcified tissue international, 36(2), 194-199 (1984-03-01)
The purpose of the present study was to investigate the mechanism of action on bone of Benzo(B)Thiophene-2-Carboxylic Acid (BL-5583). BL-5583, at a dose range of 0.01-100 micrograms/ml, inhibited spontaneous as well as A23187 and PTH-induced bone resorption in tissue culture.
J C Robin et al.
Journal of medicine, 11(1), 15-27 (1980-01-01)
Total skeletal calcium was determined in female mice with the aid of whole body neutron activation analysis. Three months treatment with heaprin produced significant osteoporosis in C3-H/St(Ha) mice but not in C57/BL6(J) mice. This was more pronounced in the younger
The synthesis of some substituted thianaphthene-2-carboxamides and their antifungal properties.
Goettsch RW and Wiese GA.
Journal of the American Pharmaceutical Association, 47(5), 319-322 (1958)
Fabrication of Carboxylated Conducting Polymer/CNTs Composites Thin Films for Immunosensor Application.
Netsuwan P, et al.
Mol. Cryst. Liq. Cryst., 580(1), 7-14 (2013)
M Nyska et al.
International journal of experimental pathology, 73(6), 733-740 (1992-12-01)
Thionaphthene-2-carboxylic acid (TNCA) has been shown to decrease osteoclast-mediated bone resorption in vitro and has shown efficacy in animal models of hypercalcaemia of malignancy. In this study, the effects of TNCA on the tibial proximal epiphysis and the sternum have
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