240850
D-sorbitol
99% (GC)
Synonyme(s) :
D-glucitol
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About This Item
Formule empirique (notation de Hill):
C6H14O6
Numéro CAS:
Poids moléculaire :
182.17
Numéro Beilstein :
1721899
Numéro CE :
Numéro MDL:
Code UNSPSC :
12352201
ID de substance PubChem :
Nomenclature NACRES :
NA.21
Produits recommandés
Densité de vapeur
<1 (vs air)
Niveau de qualité
Pression de vapeur
<0.1 mmHg ( 25 °C)
Pureté
99% (GC)
Forme
powder
Activité optique
[α]20/D +104°, c = 0.4 in acidified ammonium molybdate
Couleur
white
Plage de pH utile
5.0-7.0 (25 °C, 182 g/L)
Pf
98-100 °C (lit.)
Solubilité
water: soluble 182 g/L at 20 °C (68 °F )
Chaîne SMILES
OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CO
InChI
1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4+,5-,6-/m1/s1
Clé InChI
FBPFZTCFMRRESA-JGWLITMVSA-N
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Catégories apparentées
Application
May be used for washing spheroplasts and in isoelectric focusing to minimize endoosmotic flow in agarose gels. May be used to induce osmotic stress.
Sorbitol, a bacterial culture supplement, has been used for the preparation of selective plating media to culture Sorbitol-fermenting bacteria including strains of Escherichia coli and Yersinia enterocolitica. It has also been used as one of the ingredients to prepare Drosophila embryos for immunoelectron microscopy. It has also been used as an additive to glucuronoxylan as potential food packaging material.
Actions biochimiques/physiologiques
D-Sorbitol is a sugar alcohol that is commonly used as a sugar substitute. It occurs naturally and is also produced synthetically from glucose. The food industry uses D-sorbitol as an additive in the form of a sweetener, humectant, emulsifier, thickener, or dietary supplement. D-Sorbitol has also been found in cosmetics, paper, and pharmaceuticals. Naturally, D-sorbitol occurs widely in plants via photosynthesis, ranging from algae to higher order fruits of the family Rosaceae.
Sorbitol is a slowly metabolized sugar alcohol produced by reduction of glucose. In the polyol pathway, sorbitol is further oxidized to fructose by sorbitol dehydrogenase. Sorbitol does not diffuse easily across the cell membranes and may cause osmotic damage to the cells. The metabolism of sorbitol is most important in the pathology of diabetes related vascular complications.
Autres remarques
To gain a comprehensive understanding of our extensive range of Sugar alcohols for your research, we encourage you to visit our Carbohydrates Category page.
Code de la classe de stockage
11 - Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 1
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Équipement de protection individuelle
Eyeshields, Gloves, type N95 (US)
Certificats d'analyse (COA)
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Les clients ont également consulté
Maria Gröndahl et al.
Biomacromolecules, 5(4), 1528-1535 (2004-07-13)
Free films based on glucuronoxylan isolated from aspen wood were prepared by casting from aqueous solutions and drying in a controlled environment. Addition of xylitol or sorbitol facilitated film formation and thus examination of the material properties of these films.
Shiliang Zhang et al.
Methods in molecular biology (Clifton, N.J.), 475, 275-297 (2008-11-04)
Myoblast fusion in Drosophila has become a powerful genetic system with which to unravel the mechanisms underlying cell fusion. The identification of important components of myoblast fusion by genetic analysis has led to a molecular pathway toward our understanding of
M Brownlee
Nature, 414(6865), 813-820 (2001-12-14)
Diabetes-specific microvascular disease is a leading cause of blindness, renal failure and nerve damage, and diabetes-accelerated atherosclerosis leads to increased risk of myocardial infarction, stroke and limb amputation. Four main molecular mechanisms have been implicated in glucose-mediated vascular damage. All
J Jeffery et al.
Proceedings of the National Academy of Sciences of the United States of America, 80(4), 901-905 (1983-02-01)
A pathway from glucose via sorbitol bypasses the control points of hexokinase and phosphofructokinase in glucose metabolism. It also may produce glycerol, linking the bypass to lipid synthesis. Utilization of this bypass is favored by a plentiful supply of glucose--hence
Gregory M LaMonte et al.
Nature communications, 11(1), 1780-1780 (2020-04-15)
A promising new compound class for treating human malaria is the imidazolopiperazines (IZP) class. IZP compounds KAF156 (Ganaplacide) and GNF179 are effective against Plasmodium symptomatic asexual blood-stage infections, and are able to prevent transmission and block infection in animal models.
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