202398
Poly(éthylène glycol)
average Mn 400, hydroxyl
Synonyme(s) :
PEG
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About This Item
Formule linéaire :
H(OCH2CH2)nOH
Numéro CAS:
Numéro MDL:
Code UNSPSC :
12352104
ID de substance PubChem :
Nomenclature NACRES :
NA.23
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Nom du produit
Poly(éthylène glycol), average Mn 400
Forme
viscous liquid
Niveau de qualité
Poids mol.
Mn 380-420
average Mn 400
Caractéristiques du produit alternatif plus écologique
Safer Solvents and Auxiliaries
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sustainability
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Indice de réfraction
n20/D 1.466
pH
4.5-7.5
Viscosité
7.3 cSt(210 °F)(lit.)
Pf
4-8 °C (lit.)
Densité
1.128 g/mL
Extrémité Ω
hydroxyl
Extrémité α
hydroxyl
Autre catégorie plus écologique
Chaîne SMILES
C(CO)O
InChI
1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
Clé InChI
LYCAIKOWRPUZTN-UHFFFAOYSA-N
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Catégories apparentées
Description générale
Poly(ethylene glycol) (PEG) is a synthetic, hydrophilic, biocompatible polymer with widespread use in biomedical and other applications. PEGs are non-toxic, FDA-approved, generally non-immunogenic, and frequently used in many biomedical applications including bioconjugation, drug delivery, surface functionalization, and tissue engineering. In drug delivery, PEGs can be used as linkers for antibody-drug conjugates (ADCs) or as a surface coating on nanoparticles to improve systemic drug delivery.
Application
Poly(ethylene glycol) (PEG) has been used as a coating agent for the synthesis and in vitro safety assessment of magnetic bacterial cellulose (MBC) pellicles, performed on porcine aortic smooth muscle cells (PAOSMC). PEG provides a compatible surface for cell culture, since uncoated iron oxide NPs are considered cytotoxic to cells. It has also been used as a plasticizer in investigating the effectiveness of polyvinylpyrrolidone microneedles for transdermal delivery of functional collagen using porcine skin, adult human skin analog and human foreskin. Microneedles obtained, were reportedly characterized by various analytical and bio-analytical techniques.
Solvent for greener fluorination of acetoacetamides with Selectfluor®.
Catalyst-free and highly selective electrophilic mono-fluorination of acetoacetamides: facile and efficient preparation of 2-fluoroacetoacetamides in PEG-400
Catalyst-free and highly selective electrophilic mono-fluorination of acetoacetamides: facile and efficient preparation of 2-fluoroacetoacetamides in PEG-400
Used in conjunction with carbon black to form a conductive composite. Polymer nanospheres of poly(ethylene glycol) were used for drug delivery.
Informations légales
Selectfluor is a registered trademark of Merck KGaA, Darmstadt, Germany
Produit(s) apparenté(s)
Réf. du produit
Description
Tarif
Code de la classe de stockage
10 - Combustible liquids
Classe de danger pour l'eau (WGK)
WGK 1
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Équipement de protection individuelle
Eyeshields, Gloves
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Global Trade Item Number
| Référence | GTIN |
|---|---|
| 202398-20KG | 4061838252340 |
| 202398-5G | 4061838252357 |
| 202398-250G | 4061838764881 |
| 202398-500G | 4061838764898 |
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