124591
2-Coumaranone
97%
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About This Item
Formule empirique (notation de Hill):
C8H6O2
Numéro CAS:
Poids moléculaire :
134.13
Numéro CE :
Numéro MDL:
Code UNSPSC :
12352100
ID de substance PubChem :
Nomenclature NACRES :
NA.22
Produits recommandés
Pureté
97%
Forme
powder
Point d'ébullition
248-250 °C (lit.)
Pf
49-51 °C (lit.)
Solubilité
H2O: soluble 3.8 g/L at 30 °C
Chaîne SMILES
O=C1Cc2ccccc2O1
InChI
1S/C8H6O2/c9-8-5-6-3-1-2-4-7(6)10-8/h1-4H,5H2
Clé InChI
ACZGCWSMSTYWDQ-UHFFFAOYSA-N
Informations sur le gène
human ... CYP1A2(1544)
Catégories apparentées
Application
2-Coumaranone has been used to study the effects of coumarins on 7,12-dimethyibenz(a)anthracene induced neoplasia of the rat mammary gland. It was employed as probe for detecting enzymes which hydrolyze 2-hydroxybenzofuran structures.
Mention d'avertissement
Warning
Mentions de danger
Conseils de prudence
Classification des risques
Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1
Code de la classe de stockage
11 - Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 3
Point d'éclair (°F)
257.0 °F
Point d'éclair (°C)
125 °C
Équipement de protection individuelle
Eyeshields, Gloves, type N95 (US)
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V Strubel et al.
FEMS microbiology letters, 49(2-3), 233-238 (1989-04-01)
Dibenzofuran degrading bacteria were enriched from various environmental sources. A mutualistic mixed culture of strain DPO 220 and strain DPO 230 was characterized. Strain DPO 220 alone showed limited growth with dibenzofuran as sole source of carbon and energy (td
Inhibition of chemical carcinogen-induced neoplasia by coumarins and alpha-angelicalactone.
L W Wattenberg et al.
Cancer research, 39(5), 1651-1654 (1979-05-01)
Esa R Korpi et al.
Addiction biology, 22(4), 1022-1035 (2016-03-19)
Opioid antagonist treatments reduce alcohol drinking in rodent models and in alcohol-dependent patients, with variable efficacy across different studies. These treatments may suffer from the development of tolerance and opioid receptor supersensitivity, as suggested by preclinical models showing activation of
Eric M Jones et al.
Cell systems, 8(3), 254-260 (2019-03-25)
G protein-coupled receptors (GPCRs) are central to how mammalian cells sense and respond to chemicals. Mammalian olfactory receptors (ORs), the largest family of GPCRs, mediate the sense of smell through activation by small molecules, though for most bonafide ligands, they
Ilaria Zamparo et al.
Cell reports, 29(13), 4334-4348 (2019-12-26)
In mammals, odorant receptors not only detect odors but also define the target in the olfactory bulb, where sensory neurons project to give rise to the sensory map. The odorant receptor is expressed at the cilia, where it binds odorants
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