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Merck

PRG4

proteoglycan 4

Synonymes:
CACP, HAPO, JCAP, MSF, SZP, bG174L6.2
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(23572) Summary: The protein encoded by this gene is a large proteoglycan specifically synthesized by chondrocytes located at the surface of articular cartilage, and also by some synovial lining cells. This protein contains both chondroitin sulfate and keratan sulfate glycosaminoglycans. It functions as a boundary lubricant at the cartilage surface and contributes to the elastic absorption and energy dissipation of synovial fluid. Mutations in this gene result in camptodactyly-arthropathy-coxa vara-pericarditis syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Human(10216) Summary: The protein encoded by this gene is a large proteoglycan specifically synthesized by chondrocytes located at the surface of articular cartilage, and also by some synovial lining cells. This protein contains both chondroitin sulfate and keratan sulfate glycosaminoglycans. It functions as a boundary lubricant at the cartilage surface and contributes to the elastic absorption and energy dissipation of synovial fluid. Mutations in this gene result in camptodactyly-arthropathy-coxa vara-pericarditis syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(96875) proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein)
  • Rat(289104) proteoglycan 4
  • chicken(768493) proteoglycan 4
  • Horse(100034016) proteoglycan 4
  • domestic cat(101085684) proteoglycan 4
  • dog(664716) proteoglycan 4
  • cow(280867) proteoglycan 4
  • sheep(100294585) proteoglycan 4
  • sheep(101110076) proteoglycan 4
  • naked mole-rat(101697808) proteoglycan 4
  • Domestic Rabbit(100328909) proteoglycan 4
  • domestic guinea pig(100716004) proteoglycan 4

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anticorps anti-lubricine/protéoglycane 4, clone 9G3, clone 9G3, from mouse,
Espèces réactives
human, rat
Application
immunohistochemistry
western blot
Anti-Lubricin/PRG4 Antibody, clone 1C20 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
human, mouse, rat
Application
affinity binding assay
immunohistochemistry

western blot
Anti-Lubricin/PRG4 Antibody, clone 9G3 ZooMAb® Mouse Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
human, rat
Application
immunofluorescence
immunohistochemistry

western blot
Anti-Lubricin/Proteoglycan 4, clone 5C11 Antibody, clone 5C11, from mouse,
Espèces réactives
bovine, canine, goat, guinea pig, human, porcine, rat
Application
immunohistochemistry
western blot

Proteins

Référence du produit
Description
Espèce(s)
Proteoglycan from bovine nasal septum, chromatographically purified,
Espèce(s)
cow

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting mouse Prg4,
Espèce(s)
mouse
MISSION® esiRNA, targeting human PRG4,
Espèce(s)
human