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MMP1

matrix metallopeptidase 1 (interstitial collagenase)

Synonymes:
CLG, CLGN
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(4312) Summary: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009]
  • Rat(300339) matrix metallopeptidase 1 (interstitial collagenase)
  • Rat(432357) matrix metalloproteinase 1
  • sheep(101120355) matrix metallopeptidase 1 (interstitial collagenase)
  • domestic guinea pig(100727966) matrix metallopeptidase 1 (interstitial collagenase)
  • naked mole-rat(101697620) matrix metallopeptidase 1 (interstitial collagenase)
  • Domestic Rabbit(100009110) matrix metallopeptidase 1 (interstitial collagenase)
  • fruit fly(37949) Matrix metalloproteinase 1
  • dog(489428) matrix metallopeptidase 1 (interstitial collagenase)
  • cow(281308) matrix metallopeptidase 1 (interstitial collagenase)
  • Horse(100033896) matrix metallopeptidase 1 (interstitial collagenase)
  • chicken(418982) matrix metallopeptidase 1 (interstitial collagenase)

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ELISA

Référence du produit
Description
Espèce(s)
Human MMP-1 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Espèce(s)
human
Human MMP-1 ELISA Kit, for cell and tissue lysates,
Espèce(s)
human

Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-Matrix Metalloproteinase-1 antibody produced in goat, affinity isolated antibody, lyophilized powder,
Espèces réactives
human
Application
immunocytochemistry
immunohistochemistry

western blot
Anti-MMP-1 (Ab-1) Mouse mAb (41-1E5), liquid, clone 41-1E5, Calbiochem®,
Espèces réactives
human
Application
Anti-MMP-1 Antibody, a.a. 332-350 hMMP1, clone 41-1E5, clone 41-1E5, Chemicon®, from mouse,
Espèces réactives
human, rabbit
Application
ELISA
immunohistochemistry

western blot
Anti-MMP1 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
western blot
Anti-MMP1 antibody produced in rabbit, ,
Espèces réactives
human
Application
western blot

Small Molecule - Inhibitor

Référence du produit
Description
Espèce(s)
Doxycycline monohydrate, ,
Espèce(s)
human
Doxycycline Monohydrate, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human
2,2′:5′,2′′:5′′,2′′′-Quaterthiophene, 96%,
Espèce(s)
human, rat, mouse
Marimastat, ≥98% (HPLC),
Espèce(s)
human, rat, mouse
CP-101537, ≥98% (HPLC),
Espèce(s)
human, rat, mouse

Proteins

Référence du produit
Description
Espèce(s)
MMP-1 human, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Espèce(s)
human
Matrix Metalloproteinase-1 human, recombinant, expressed in NSO cells, >95% (SDS-PAGE), buffered aqueous solution,
Espèce(s)
human
Collagen Type I−FITC Conjugate from bovine skin, ~1 mg/mL, solution,
Espèce(s)
cow, rat, human, mouse

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human MMP1,
Espèce(s)
human