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Merck

CHRNB3

cholinergic receptor, nicotinic, beta 3 (neuronal)

Synonymes:
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(1142) Summary: The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are (hetero)pentamers composed of homologous subunits. The subunits that make up the muscle and neuronal forms of nAChRs are encoded by separate genes and have different primary structure. There are several subtypes of neuronal nAChRs that vary based on which homologous subunits are arranged around the central channel. They are classified as alpha-subunits if, like muscle alpha-1 (MIM 100690), they have a pair of adjacent cysteines as part of the presumed acetylcholine binding site. Subunits lacking these cysteine residues are classified as beta-subunits (Groot Kormelink and Luyten, 1997 [PubMed 9009220]
  • Mouse(108043) cholinergic receptor, nicotinic, beta polypeptide 3
  • Rat(171131) cholinergic receptor, nicotinic, beta 3 (neuronal)
  • chicken(395604) cholinergic receptor, nicotinic, beta 3 (neuronal)
  • cow(521702) cholinergic receptor, nicotinic, beta 3 (neuronal)
  • Horse(100054095) cholinergic receptor, nicotinic, beta 3 (neuronal)
  • dog(482837) cholinergic receptor, nicotinic, beta 3 (neuronal)
  • domestic cat(101098624) cholinergic receptor, nicotinic, beta 3 (neuronal)
  • sheep(101122833) cholinergic receptor, nicotinic, beta 3 (neuronal)
  • Domestic Rabbit(100355898) cholinergic receptor, nicotinic, beta 3 (neuronal)
  • naked mole-rat(101706291) cholinergic receptor, nicotinic, beta 3 (neuronal)
  • domestic guinea pig(100723424) cholinergic receptor, nicotinic, beta 3 (neuronal)

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Small Molecule - Agonist

Référence du produit
Description
Espèce(s)
Decamethonium bromide, crystalline,
Espèce(s)
human
1,1-Dimethyl-4-phenylpiperazinium iodide, ≥98% (TLC or titration),
Espèce(s)
human, rat

Small Molecule - Antagonist

Référence du produit
Description
Espèce(s)
Mecamylamine hydrochloride, ,
Espèce(s)
human
1,1-Dimethyl-4-phenylpiperazinium iodide, ≥98% (TLC or titration),
Espèce(s)
human, rat
Acide kynurénique, ≥98%,
Espèce(s)
rat, human

Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-CHRNB3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
Anti-CHRNB3 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
human, mouse, rat
Application
ELISA
western blot

Small Molecule - Blocker

Référence du produit
Description
Espèce(s)
Tetraethylammonium chloride, ≥98% (titration),
Espèce(s)
human
Hexamethonium bromide, ,
Espèce(s)
human
Hexamethonium chloride, solid (hygroscopic),
Espèce(s)
human
Acide kynurénique, ≥98%,
Espèce(s)
rat, human

Proteins

Référence du produit
Description
Espèce(s)
Buserelin acetate salt, ≥90% (HPLC),
Espèce(s)
rat