731099

N-(3-Aminopropyl)methacrylamide hydrochloride

contains ≤1,000 ppm MEHQ as stabilizer, 98% (HPLC)

• Synonym(s): APMA
• Empirical Formula (Hill Notation): C₇H₁₄N₂O · HCl
• CAS Number: 72607-53-5
• Molecular Weight: 178.66
• MDL number: MFCD00078257
• UNSPSC Code: 12162002
• PubChem Substance ID: 329764619
• NACRES: NA.23

Properties

• Assay: 98% (HPLC)
• form: powder
• contains: ≤1,000 ppm MEHQ as stabilizer
• mp: 123-128 °C
• storage temp.: 2-8°C
• SMILES string: Cl.CC(=C)C(=O)NCCCN
• InChI: 1S/C7H14N2O.ClH/c1-6(2)7(10)9-5-3-4-8;/h1,3-5,8H2,2H3,(H,9,10);1H
• InChI key: XHIRWEVPYCTARV-UHFFFAOYSA-N

Description

General description

N-(3-Aminopropyl)methacrylamide hydrochloride (APMA) is an aminoalkyl methacrylamide which can be synthesized by adding 1,3-diaminopropane to 1,3-diaminopropane dihydrogen chloride solution and further mixing the solution with methacrylic anhydride and hydroquinone. It has a primary amine that provides attractive features such as pH-responsiveness, affinity for anionic drugs and conjugation for variety of chemical structures.

Application

APMA can be used in the preparation of copolymers and cross-linked miscellas for gene delivery, drug delivery and diagnostics applications.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H319
• Precautionary Statements: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Eye Irrit. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable