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702455

Sigma-Aldrich

1H-Indazole-5-carboxylic acid

97%

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About This Item

Empirical Formula (Hill Notation):
C8H6N2O2
CAS Number:
61700-61-6
Molecular Weight:
162.15
MDL number:
MFCD06804570
UNSPSC Code:
12352100
PubChem Substance ID:
329762377
NACRES:
NA.22

Quality Level

100

Assay

97%

form

powder

mp

318-322 °C

functional group

carboxylic acid

SMILES string

OC(=O)c1ccc2[nH]ncc2c1

InChI

1S/C8H6N2O2/c11-8(12)5-1-2-7-6(3-5)4-9-10-7/h1-4H,(H,9,10)(H,11,12)

InChI key

MAVGBUDLHOOROM-UHFFFAOYSA-N

Related Categories

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCG9067
MKCB7416
MKBQ5065V
MKBG8884V
MKBB6295

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Patrick Grailhe et al.
FEBS open bio, 10(10), 2010-2020 (2020-08-19)
Sphingosine-1 phosphate receptor-1 (S1P1 ) activation maintains endothelial barrier integrity, whereas S1P1 desensitization induces peripheral blood lymphopenia. The latter is exploited in the approval and/or late-stage development of receptor-desensitizing agents targeting the S1P1 receptor in multiple sclerosis, such as siponimod
Nikolay T Tzvetkov et al.
European journal of medicinal chemistry, 127, 470-492 (2017-01-21)
The pharmacological and physicochemical analysis of structurally optimized N-alkyl-substituted indazole-5-carboxamides, developed as potential drug and radioligand candidates for the treatment and diagnosis of Parkinson's disease (PD) and other neurological disorders, is reported. Recent efforts have been focused on the development

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