1173508

Desoximetasone

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): 9-Fluoro-11β,21-dihydroxy-16α-methylpregna-1,4-diene-3,20-dione
• Empirical Formula (Hill Notation): C₂₂H₂₉FO₄
• CAS Number: 382-67-2
• Molecular Weight: 376.46
• MDL number: MFCD00083301
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• biological source: synthetic
• Agency: USP
• vapor pressure: <0.0000001 kPa ( 25 °C)
• API family: desoximetasone
• form: powder
• packaging: pkg of 200 mg
• manufacturer/tradename: USP
• storage condition: protect from light
• color: white
• solubility: acetone: freely soluble; alcohol: freely soluble; benzene: slightly soluble; chloroform: freely soluble; ether: slightly soluble; water: insoluble
• application(s): pharmaceutical (small molecule)
• SMILES string: [H][C@@]12C[C@@H](C)[C@H](C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]3(F)[C@@]2([H])CCC4=CC(=O)C=C[C@]34C
• InChI: 1S/C22H29FO4/c1-12-8-16-15-5-4-13-9-14(25)6-7-21(13,3)22(15,23)18(27)10-20(16,2)19(12)17(26)11-24/h6-7,9,12,15-16,18-19,24,27H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,18+,19-,20+,21+,22+/m1/s1
• InChI key: VWVSBHGCDBMOOT-IIEHVVJPSA-N
• Gene Information: human ... NR3C1(2908)

Description

General description

Desoximetasone is a topical corticosteroid known to modify the functions of leukocytes that are mainly responsible for skin infections, inflammation and allergies.

Application

Desoximetasone is used as an analytical standard for the determination of the analyte in pharmaceutical dosage forms by various analytical techniques.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• Pictograms: GHS07,GHS08
• Signal Word: Warning
• Hazard Statements: H302 + H312 + H332 - H315 - H317 - H319 - H335 - H351
• Precautionary Statements: P201 - P280 - P301 + P312 + P330 - P302 + P352 + P312 - P304 + P340 + P312 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable