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Key Documents

G005691

LC/MS Analysis of CYP2D6 Inhibitors on Ascentis® Express HILIC

application for HPLC

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About This Item

technique(s)

HPLC: suitable

test parameters

column: Ascentis Express HILlC, 10 cm x 2.1 mm I.D., 2.7 μm particles (53939-U)
mobile phase: 5 mM ammonium formate in 2:98 (v/v) water:acetonitrile
flow rate: 1.2 mL/min
column temp.: 50 °C
detector: ESI(+), m/z 100-400
injection: 0.5 μL

suitability

application for HPLC

application(s)

clinical
life science and biopharma

Analysis Note

This application demonstrates the suitability of the Ascentis Express HILIC for the analysis of CYP2D6 Inhibitors.

Legal Information

Ascentis is a registered trademark of Merck KGaA, Darmstadt, Germany

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Description

    Imipramine

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