SML3823
KCI807
≥98% (HPLC)
Synonym(s):
5,3’-Dihydroxyflavone, 5-Hydroxy-2-(3-hydroxyphenyl)-4H-1-benzopyran-4-one
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About This Item
Empirical Formula (Hill Notation):
C15H10O4
CAS Number:
Molecular Weight:
254.24
MDL number:
UNSPSC Code:
51111800
UNSPSC Code:
12352200
NACRES:
NA.77
Recommended Products
Quality Level
Assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
0.2 mg/mL (DMSO:EtOH (2:1),clear, warmed, clear colorless solution)
storage temp.
room temp
Biochem/physiol Actions
KCI807 is a cell penetrant, selective and potent inhibitor of the androgen receptor (AR)-ELK1 interaction. KCI807 interrupts association of the androgen receptor (AR) with transcription activator ELK1 (ETS family transcription factor ELK1). It potently suppresses growth of enzalutamide-resistant prostate cancer tumor xenografts in rodents.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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