SML0067
IOX1
≥97% (HPLC)
Synonym(s):
5-Carboxy-8-hydroxyquinoline, 8-Hydroxy-5-quinolinecarboxylic acid
About This Item
Recommended Products
Assay
≥97% (HPLC)
form
powder
color
white to brown
solubility
DMSO: 10 mg/mL, clear
storage temp.
2-8°C
SMILES string
OC(=O)c1ccc(O)c2ncccc12
InChI
1S/C10H7NO3/c12-8-4-3-7(10(13)14)6-2-1-5-11-9(6)8/h1-5,12H,(H,13,14)
InChI key
JGRPKOGHYBAVMW-UHFFFAOYSA-N
Related Categories
Application
- To eliminate viral latency in latent viruses in order to sensitize the viral infections to antiviral therapy.
- In histone lysine demethylase 4A (KDM4A) inhibition, to serve as a unique strategy to decrease hypoxia-inducible factors signalling.
- to restore oncogene-induced senescence in wild-type mouse embryo fibroblasts.
Biochem/physiol Actions
To learn about other SGC chemical probes for epigenetic targets, visit sigma.com/sgc
Features and Benefits
related product
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Epigenetic modifications are thought to occur through two key interconnected processes—DNA methylation and the covalent modification of histones.
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