SAB4200879
Anti-DDX6-Alexa488 antibody, Mouse monoclonal
clone DDX6-34, purified from hybridoma cell culture
Synonym(s):
ATP-dependent RNA helicase p54, DEAD box protein 6, HLR2, Oncogene RCK, Probable ATP-dependent RNA helicase DDX6
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Biochem/physiol Actions
Viruses like Hepatitis C virus (HCV) or West Nile virus (WNV) utilize the host cell DDX6 to promote virus infection by recruiting it to the viral replication sites where it is involved in stabilization of the viral genome and the shift between translation and replication.2,5-6
DDX6 was reported to be overexpressed in colorectal adenocarcinomas, gastric cancer and in most malignant cell lines.7-9 It was suggested that DDX6 acted as an upstream cancerous enhancer through RNA-binding of HER2 and FGFR2 mRNAs that positively regulates post-transcriptional processes in cancer cells.7
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12 - Non Combustible Liquids
WGK
nwg
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