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Key Documents

SAB2702144

Sigma-Aldrich

Monoclonal Anti-POLD1 antibody produced in mouse

Synonym(s):

CDC2, POLD

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

mouse

Quality Level

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

607
monoclonal

form

liquid

species reactivity

human, mouse

concentration

1 mg/mL

technique(s)

western blot: 1:1000

isotype

IgG

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... POLD1(5424)

Immunogen

Recombinant protein encoding amino acids 1-140 of the large subunit of human DNA polymerase d.

Application

For WB: Use at a concentration of 1:1,000. Predicted molecular weight: 130 kDa. Optimal dilutions/concentrations should be determined by the reseracher.

Biochem/physiol Actions

DNA polymerase d (delta) functions in DNA replication and DNA repair. It also possesses 3′ to 5′ exonuclease activity. In leading strand synthesis it requires the processivity factor, PCNA. It is also possibly involved in the completion of DNA synthesis during Okazaki fragment elongation following the initiation of synthesis by the DNA polymerase a/primase complex

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Phosphate-buffered saline, pH 7.2, containing no preservatives

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Feng Jiao et al.
Oncology reports, 32(6), 2485-2492 (2014-10-02)
Pancreatic cancer is one of the most aggressive solid malignancies with a dismal survival rate. Recent studies have shown that high expression levels of long noncoding RNA (lncRNA) metastasis-associated lung adenocarcinoma transcript-1 (MALAT-1) correlate with several solid tumors. However, the

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