Skip to Content
Merck
All Photos(5)

Key Documents

View All Documentation

P3655

Sigma-Aldrich

Poly-L-ornithine hydrobromide

suitable for cell culture, Mol wt 30,000-70,000

Synonym(s):

L-Ornithine homopolymer hydrobromide

Sign Into View Organizational & Contract Pricing
All Photos(5)

About This Item

CAS Number:
27378-49-0
MDL number:
MFCD00237231
UNSPSC Code:
12352209
NACRES:
NA.26

product name

Poly-L-ornithine hydrobromide, mol wt 30,000-70,000

form

powder

Quality Level

200

mol wt

30,000-70,000

technique(s)

cell culture | mammalian: suitable

color

white to off-white

storage temp.

−20°C

InChI

1S/C5H12N2O2.BrH/c6-3-1-2-4(7)5(8)9;/h4H,1-3,6-7H2,(H,8,9);1H

InChI key

GWRQMKDBBHFVIZ-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

Application

Poly-L-ornithine hydrobromide has been used to coat coverslips in culture vessels for culturing neural progenitor cells. It has also been used to coat culture plates for culturing cerebral cells of mice.

Biochem/physiol Actions

Poly-L-ornithine is a specialized coating that acts as a charge modifier. It is a polycationic synthetic amino acid polymer. It boosts nasal absorption of hydrophilic macromolecular drugs.

Analysis Note

Molecular weight based on viscosity. Also assayed by MALLS.

Other Notes

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Preparation and Evaluation of PEGylated Poly-L-ornithine Complex as a Novel Absorption Enhancer
Yusuke Kamiya
Biologicals : Journal of the International Association of Biological Standardization (2017)
Isolation, characterization, and differentiation of multipotent neural
progenitor cells from human cerebrospinal fluid in fetal
cystic myelomeningocele
Mario Marotta
Stem Cell Research (2017)
FGF2 and Insulin Signaling Converge to Regulate Cyclin D Expression in Multipotent Neural Stem Cells
Adedamola Adepoju
Stem Cell Research (2013)
Elena Maria Boggio et al.
Molecular neurobiology, 56(9), 5987-5997 (2019-02-02)
Perineuronal nets (PNNs) are condensed structures in the extracellular matrix that mainly surround GABA-ergic parvalbumin-positive interneurons in the adult brain. Previous studies revealed a parallel between PNN formation and the closure of the critical period. Moreover, ocular dominance plasticity is
S K Tam et al.
Acta biomaterialia, 7(4), 1683-1692 (2010-12-15)
There is a need for better understanding of the biocompatibility of alginate-polycation microcapsules based on their physicochemical characteristics. Microcapsules composed of alginate with 44% (IntG) or 71% (HiG) guluronate, gelled with calcium (Ca) or barium (Ba) and coated with poly-L-lysine
View All Related Papers

Articles

L-Ornithine in Cell Culture

Discover L-ornithine, an important amino acid supplement, explore how L-ornithine is used in CHO and iPSC culture, and discover how poly-L-ornithine is used to enhance cell attachment.

Poly(Amino Acid) Block Copolymers for Drug Delivery and other Biomedical Applications

Humankind has utilized protein materials throughout its existence, starting with the use of materials such as wool and silk for warmth and protection from the elements and continuing with the use of recombinant DNA techniques to synthesize proteins with unique and useful properties.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service