All Photos(1)

Key Documents

COO/COA

Glucose-6-phosphate Dehydrogenase from baker′s yeast (S. cerevisiae)

Name: Glucose-6-phosphate Dehydrogenase from baker′s yeast (<I>S. cerevisiae</I>)
Brand: SIGMA

Type VII, ammonium sulfate suspension, ≥200 units/mg protein

Synonym(s):

glucose-6-phosphate dehydrogenase (NADP+), G-6-P-DH, Zwischenferment

Sign Into View Organizational & Contract Pricing

All Photos(1)

About This Item

CAS Number:

9001-40-5

Enzyme Commission number:

1.1.1.49 (BRENDA, IUBMB)

EC Number:

232-602-6

MDL number:

MFCD00081656

UNSPSC Code:

12352204

NACRES:

NA.54

biological source

bakers yeast

type

Type VII

form

ammonium sulfate suspension

specific activity

≥200 units/mg protein

mol wt

128 kDa

technique(s)

cell based assay: suitable

solubility

water: soluble

application(s)

diagnostic assay manufacturing

storage temp.

2-8°C

Gene Information

Saccharomyces cerevisiae ... ZWF1(855480)

Looking for similar products? Visit Product Comparison Guide

Related Categories

Chemistry & Biochemicals

Phosphates

General description

Glucose 6-phosphate dehydrogenase (G-6-P-DH) is a key regulatory enzyme in the first step of the pentose phosphate pathway. G-6-P-DH is a glycoprotein with a molecular mass of 128 kDa (gel filtration).

Application

Glucose-6-phosphate dehydrogenase has been used in a study to investigate the effect of dehydroepiandrosterone on cell growth and mitochondrial function in TM-3 cells. Glucose-6-phosphate dehydrogenase has also been used in a study to investigate the incidence of apoptosis and transcript abundance in bovine follicular cells. Glucose-6-phosphate dehydrogenase is used to test ketose reductase activity in developing maize endosperm.

Biochem/physiol Actions

Glucose-6-phosphate dehydrogenase catalyzes the conversion of glucose-6-phosphate to 6-phosphogluconolacetone as the first step in the pentose phosphate pathway.

Unit Definition

One unit will oxidize 1.0 μmole of D-glucose 6-phosphate to 6-phospho-D-gluconate per min in the presence of NADP at pH 7.4 at 25 °C.

Physical form

Crystalline suspension in 3.2 M (NH₄)₂SO₄ solution, pH 7.0

Pictograms

GHS08

Signal Word

Danger

Hazard Statements

H334

Precautionary Statements

P261 - P284 - P501

Hazard Classifications

Resp. Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Effect of dehydroepiandrosterone on cell growth and mitochondrial function in TM-3 cells.

Xuehuai Shen et al.

General and comparative endocrinology, 177(1), 177-186 (2012-04-03)

Dehydroepiandrosterone (DHEA), a major steroid hormone, decreases with age, and this reduction has been shown to be associated with physical health. In the present study, the effect of DHEA on cell growth and mitochondrial function was investigated using TM-3 cells

Incidence of apoptosis and transcript abundance in bovine follicular cells is associated with the quality of the enclosed oocyte.

D Janowski et al.

Theriogenology, 78(3), 656-669 (2012-05-15)

The close contact and interaction between the oocyte and the follicular environment influence the establishment of oocyte developmental competence. Moreover, it is assumed that apoptosis in the follicular cells has a beneficial influence on the developmental competence of oocytes. The

Knockdown of glucose-6-phosphate dehydrogenase (G6PD) following cerebral ischemic reperfusion: the pros and cons.

Gang Zhao et al.

Neurochemistry international, 61(2), 146-155 (2012-05-15)

NADPH derived from glucose-6-phosphate dehydrogenase (G6PD), the rate-limiting enzyme of the pentose phosphate pathway, has been implicated not only to promote reduced glutathione (GSH) but also enhance oxidative stress in specific cellular conditions. In this study, the effects of G6PD

Laboratory Evolution and Reverse Engineering of Clostridium thermocellum for Growth on Glucose and Fructose.

Johannes Yayo et al.

Applied and environmental microbiology, 87(9) (2021-02-21)

The native ability of Clostridium thermocellum to efficiently solubilize cellulose makes it an interesting platform for sustainable biofuel production through consolidated bioprocessing. Together with other improvements, industrial implementation of C. thermocellum, as well as fundamental studies into its metabolism, would

Application of high-throughput transcriptomics for mechanism-based biological read-across of short-chain carboxylic acid analogues of valproic acid.

Nanette G Vrijenhoek et al.

ALTEX, 39(2), 207–220-207–220 (2022-01-19)

Chemical read-across is commonly evaluated without specific knowledge of the biological mechanisms leading to observed adverse outcomes in vivo. Integrating data that indicate shared modes of action in humans will strengthen read-across cases. Here we studied transcriptomic responses of primary

View All Related Papers

Articles

How to Work with Enzymes Supplied as Ammonium Sulfate Suspensions

Instructions for working with enzymes supplied as ammonium sulfate suspensions

Protocols

Enzymatic Assay of Glucose-6-Phosphate Dehydrogenase (EC 1.1.1.49)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service