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Key Documents

F3510

Sigma-Aldrich

D-(−)-Fructose

≥99% (HPLC), BioReagent, suitable for cell culture, suitable for insect cell culture

Synonym(s):

D-Levulose, Fruit sugar

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About This Item

Empirical Formula (Hill Notation):
C6H12O6
CAS Number:
Molecular Weight:
180.16
Beilstein:
1239004
EC Number:
MDL number:
UNSPSC Code:
12352201
PubChem Substance ID:
NACRES:
NA.21

biological source

corn

product line

BioReagent

Assay

≥99% (HPLC)

form

powder

optical activity

[α]25/D -91.3 to -87.7 °, c = 5% (w/v) in water

technique(s)

cell culture | insect: suitable
cell culture | mammalian: suitable

impurities

≤0.05% Glucose (enzymatic)

color

colorless

useful pH range

5.0-7.0 (25 °C, 18 g/L)

mp

119-122 °C (dec.) (lit.)

solubility

790 g/L at 20 °C

SMILES string

OC[C@@H](O)[C@@H](O)[C@H](O)C(=O)CO

InChI

1S/C6H12O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3,5-9,11-12H,1-2H2/t3-,5-,6-/m1/s1

InChI key

BJHIKXHVCXFQLS-UYFOZJQFSA-N

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General description

Fructose is a monosaccharide. It is present in fruits and vegetables. Fructose is the major carbohydrate in the diet. It binds with glucose to form sucrose. Excessive intake of fructose is associated with obesity, type 2 diabetes and cardiovascular disease.

Application

D-(-)-Fructose has been used for metabolite determination. It has also been used as a component of cultural media.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Nutritional Biochemistry (1999)
Fructose and cardiometabolic health: what the evidence from sugar-sweetened beverages tells us
Malik VS and Hu FB
Journal of the American College of Cardiology, 66(14), 1615-1624 (2015)
Comparative metabolic analysis of CHO cell clones obtained through cell engineering, for IgG productivity, growth and cell longevity
Wilkens CA and Gerdtzen ZP
Testing, 10(3), e0119053-e0119053 (2015)
Camila A Wilkens et al.
PloS one, 10(3), e0119053-e0119053 (2015-03-15)
Cell engineering has been used to improve animal cells' central carbon metabolism. Due to the central carbon metabolism's inefficiency and limiting input of carbons into the TCA cycle, key reactions belonging to these pathways have been targeted to improve cultures'
Streamlined duplex live-dead microplate assay for cultured cells
Pfeffer BA and Fliesler SJ
Experimental Eye Research, 161, 17-29 (2017)

Articles

Glucose metabolism is regulated by the opposing actions of insulin and glucagon. Insulin is released from pancreatic ß cells in response to high blood glucose levels and regulates glucose metabolism through its actions on muscle, liver, and adipose tissue.

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