E1904
Ethyl-3,4-dephostatin
>99% (HPLC), solid
Synonym(s):
3,4-Dihydroxy-N-ethyl-N-nitrosoaniline
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About This Item
Empirical Formula (Hill Notation):
C8H10N2O3
CAS Number:
Molecular Weight:
182.18
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
Recommended Products
Quality Level
Assay
>99% (HPLC)
form
solid
color
brown
solubility
DMSO: soluble 22 mg/mL
H2O: soluble 8 mg/mL
storage temp.
2-8°C
SMILES string
CCN(N=O)c1ccc(O)c(O)c1
InChI
1S/C8H10N2O3/c1-2-10(9-13)6-3-4-7(11)8(12)5-6/h3-5,11-12H,2H2,1H3
InChI key
ZTXUSFPBLYQDDN-UHFFFAOYSA-N
Biochem/physiol Actions
Stable analog of dephostatin. Selective inhibitor of protein tyrosine phosphatase 1B and SHPTP-1. Does not inhibit CD45-associated phosphatases.
Features and Benefits
This compound is featured on the Phosphoprotein Phosphatases (Tyrosine) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Caution
Store under nitrogen
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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J H Kim et al.
Cell death & disease, 4, e588-e588 (2013-04-13)
Hypoxia enhances the proliferation and migration of adipose-derived stem cells (ASCs) via the generation of reactive oxygen species (ROS). Therefore, this study primarily investigated whether or not ROS generation could regulate microRNA-210 (miR-210) expression, and increase proliferation/migration of ASCs. In
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